Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | AHCY | P23526 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997084 | 0.85 | ADORA2A (0.43) | ADORA2AADORA1ADORA2BAHCYSMN1; SMN2 | |
| 3-Ethyladenine SCHEMBL48200 | 0.78 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BAHCYLMNA | |
| SCHEMBL16038118 | 0.78 | CYP3A4 (0.47) | ADORA2AADORA1CYP3A4 | |
| SCHEMBL9108201 | 0.76 | ADORA2A (0.36) | ADORA2AADORA1ADORA2BAHCYLMNA | |
| 3-Propyladenine SCHEMBL15756434 | 0.76 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BLMNASMN1; SMN2 | |
| SCHEMBL5513295 | 0.75 | ADORA2A (0.35) | ADORA2AADORA1ADORA2BAHCYLMNA | |
| SCHEMBL16038063 | 0.75 | CYP3A4 (0.46) | CYP3A4 | |
| SCHEMBL11289245 | 0.75 | L3MBTL1 (0.41) | ADORA2AADORA1AHCYLMNASMN1; SMN2 | |
| SCHEMBL11283124 | 0.75 | L3MBTL1 (0.41) | ADORA2AADORA1AHCYLMNASMN1; SMN2 | |
| SCHEMBL16037421 | 0.75 | CYP3A4 (0.46) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358968-B | Preparation method of tenofovir | 科兴生物制药股份有限公司 | 2020-09-15 | — | — | CN | disclosed |
| CN-108358968-A | A kind of preparation method of high-purity tenofovir | 山东科兴生物制品有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-104230934-B | A kind of compound and its production and use | 上海医药工业研究院 | 2016-12-28 | — | — | CN | disclosed |