Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.34 |
| ▸ | PNP | P00491 | 4/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28350467 | 0.82 | FGFR1 (0.64) | FGFR1SLC22A6ENPP1CYP3A4HPRT1 | |
| SCHEMBL8927904 | 0.79 | SLC22A6 (0.70) | FGFR1SLC22A6ENPP1CYP3A4NT5E | |
| SCHEMBL8897180 | 0.78 | SLC22A6 (0.72) | FGFR1SLC22A6ENPP1CYP3A4NT5E | |
| SCHEMBL8895414 | 0.77 | SLC22A6 (0.70) | FGFR1SLC22A6ENPP1CYP3A4NT5E | |
| SCHEMBL16038118 | 0.70 | CYP3A4 (0.47) | FGFR1SLC22A6CYP3A4 | |
| SCHEMBL19064885 | 0.70 | CYP3A4 (0.47) | FGFR1SLC22A6CYP3A4 | |
| SCHEMBL16037421 | 0.69 | CYP3A4 (0.46) | FGFR1SLC22A6CYP3A4 | |
| SCHEMBL16038063 | 0.69 | CYP3A4 (0.46) | FGFR1SLC22A6CYP3A4 | |
| SCHEMBL8708627 | 0.68 | FDPS (0.59) | FGFR1SLC22A6ENPP1CYP3A4HPRT1 | |
| SCHEMBL16039557 | 0.68 | CYP3A4 (0.45) | FGFR1SLC22A6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726174-A | VIRICIDES, ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-03-10 | — | — | US | disclosed |
| US-5696265-A | ANTIRETROVIRAL; ANTITUNOR AGENT | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-12-09 | — | — | US | disclosed |
| US-5688778-A | VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-11-18 | — | — | US | disclosed |
| US-5686611-A | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-11-11 | — | — | US | disclosed |