Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16040316 | 0.85 | GRM4 (0.58) | GRM4KCNH2EGLN1KDRKDM4E | |
| SCHEMBL21129389 | 0.85 | GRM4 (0.50) | GRM4EGLN1KDM4EALDH1A1HPGD | |
| SCHEMBL29664269 | 0.75 | GRM4 (0.48) | GRM4MAP4K4TP53 | |
| SCHEMBL16039945 | 0.74 | MAP4K4 (0.48) | GRM4MAP4K4EGLN1KDM4EALDH1A1 | |
| SCHEMBL16039872 | 0.72 | MAP4K4 (0.52) | GRM4MAP4K4PDE3BPDE3AKCNH2 | |
| SCHEMBL2411655 | 0.71 | GRM4 (0.44) | GRM4EGLN1KDM4EALDH1A1HPGD | |
| SCHEMBL27687615 | 0.70 | EGLN1 (0.60) | GRM4EGLN1 | |
| SCHEMBL12410455 | 0.69 | MAP4K4 (0.52) | GRM4MAP4K4KCNH2KDRMELK | |
| SCHEMBL694374 | 0.68 | MAP4K4 (0.58) | GRM4MAP4K4KCNH2GRIN2BEGLN1 | |
| SCHEMBL22952500 | 0.68 | GRM4 (0.44) | GRM4EGLN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763449-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2017-09-19 | — | — | US | claimed |
| US-20160302415-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-10-20 | — | — | US | claimed |
| US-9402397-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-08-02 | — | — | US | claimed |
| US-20160007605-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-01-14 | — | — | US | claimed |
| US-10398144-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2019-09-03 | — | — | US | disclosed |
| US-10398144-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2019-09-03 | — | — | US | disclosed |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-9763449-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-9763449-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-9763449-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160007605-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-01-14 | — | — | US | disclosed |
| US-9173401-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-9173401-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-9173401-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2015-11-03 | — | — | US | disclosed |
| WO-2014152115-A1 | N-,C-DISUBSTITUTED AZOLES FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007605-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | CYCS, DNPH1, DDT | GRM4 2552/4885MAP4K4 4372/4885PDE3B 832/4885 |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | CYCS, DNPH1, DDT | GRM4 2552/4885MAP4K4 4372/4885PDE3B 832/4885 |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | CYCS, DNPH1, DDT | GRM4 2552/4885MAP4K4 4372/4885PDE3B 832/4885 |
| US-10398144-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | CYCS, DNPH1, DDT | GRM4 2552/4885MAP4K4 4372/4885PDE3B 832/4885 |
| US-20160302415-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | CYCS, DNPH1, DDT | GRM4 2552/4885MAP4K4 4372/4885PDE3B 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.