Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16040316 | 0.82 | GRM4 (0.58) | GRM4LMNATP53MEN1TSHR | |
| SCHEMBL23144521 | 0.77 | MKNK1 (0.50) | GRM4MAP4K4MEN1PSIP1AXL | |
| SCHEMBL29664328 | 0.77 | MKNK1 (0.50) | GRM4MAP4K4MEN1PSIP1AXL | |
| SCHEMBL23144535 | 0.76 | MAOA (0.53) | GRM4MAP4K4LMNAMEN1PSIP1 | |
| SCHEMBL29664332 | 0.76 | MAOA (0.53) | GRM4MAP4K4LMNAMEN1PSIP1 | |
| SCHEMBL16039629 | 0.75 | GRM4 (0.51) | GRM4MAP4K4TP53 | |
| SCHEMBL23144559 | 0.74 | MAOA (0.55) | MAP4K4LMNAMEN1PSIP1AXL | |
| SCHEMBL23144544 | 0.72 | GRM4 (0.47) | GRM4MAP4K4MEN1PSIP1AXL | |
| SCHEMBL23144576 | 0.72 | MAP4K4 (0.44) | GRM4MAP4K4TP53MEN1PSIP1 | |
| SCHEMBL29664194 | 0.72 | MAP4K4 (0.44) | GRM4MAP4K4TP53MEN1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728909-A | Composition for preventing or treating cancer comprising novel trifluoromethylphenylpyrazole derivative as active ingredient | 韩国原子力医学院 | 2022-07-08 | — | — | CN | disclosed |