Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859128 | 0.85 | HTR6 (0.50) | HTR6NQO2MTNR1AMTNR1BHTR7 | |
| SCHEMBL6683869 | 0.82 | HTR6 (0.47) | HTR6ADRB2NQO2MTNR1AMTNR1B | |
| SCHEMBL2338975 | 0.81 | HTR6 (0.56) | HTR6NQO2MTNR1AMTNR1BHTR7 | |
| SCHEMBL31121639 | 0.81 | HTR6 (0.56) | HTR6NQO2MTNR1AMTNR1BHTR7 | |
| SCHEMBL23023190 | 0.80 | GAA (0.53) | HTR6CHRM2SIGMAR1 | |
| SCHEMBL29663816 | 0.79 | HTR6 (0.47) | HTR6HTR7CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20430497 | 0.79 | HTR6 (0.47) | HTR6HTR7CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3874874 | 0.77 | HTR6 (0.53) | HTR6NQO2MTNR1AMTNR1BHTR7 | |
| SCHEMBL3868123 | 0.77 | HTR6 (0.53) | HTR6NQO2MTNR1AMTNR1BHTR7 | |
| SCHEMBL6552816 | 0.77 | HTR6 (0.53) | HTR6MTNR1AMTNR1BHTR7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150291567-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | GFBIOCHEMICALS LIMITED (MT) | 2015-10-15 | — | — | US | disclosed |
| US-20140135455-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2014-05-15 | — | — | US | disclosed |
| US-8653223-B2 | Transketalized compositions, synthesis, and applications | SEGETIS, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-20110082264-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| WO-2009146202-A2 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135455-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | TKT, KHK, KYAT3 | HTR6 2322/4885ADRB2 4360/4885NQO2 3069/4885 |
| US-20110082264-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | TKT, KHK, KYAT3 | HTR6 2322/4885ADRB2 4360/4885NQO2 3069/4885 |
| US-20150291567-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | TKT, KHK, KYAT3 | HTR6 2322/4885ADRB2 4360/4885NQO2 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.