Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.77 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | APP | P05067 | 1/20 | 0.72 |
| ▸ | GSK3B | P49841 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436361 | 1.00 | CYP1A1 (0.77) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL31436369 | 1.00 | CYP1A1 (0.77) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL1322027 | 0.88 | CYP1A1 (0.82) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL1322029 | 0.88 | CYP1A1 (0.82) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL20570877 | 0.87 | CYP1A1 (0.82) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL979408 | 0.87 | CYP1B1 (1.00) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL9503680 | 0.87 | CYP1B1 (1.00) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL3024151 | 0.86 | CYP1B1 (0.75) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL2705060 | 0.86 | MAPT (1.00) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 | |
| SCHEMBL9804079 | 0.86 | MAPT (1.00) | CYP1A1CYP1A2CYP1B1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242144-B2 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-08-14 | — | — | US | disclosed |
| US-20110082176-A1 | Stilbenes and Chalcones for the Prevention and Treatment of Cardiovascular Diseases | RESVERLOGIX CORP. | 2011-04-07 | — | — | US | disclosed |
| US-7846915-B2 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | Resverlogix Corporation (CA) | 2010-12-07 | — | — | US | disclosed |
| US-20060205792-A1 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | HEPALINK (HONG KONG) LIMITED (HK) | 2006-09-14 | — | — | US | disclosed |
| WO-2006045010-A2 | STILBENES AND CHALCONES FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. (CA) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205792-A1 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | APOB, APOL1, HDLBP | CYP1A1 217/4885CYP1A2 808/4885CYP1B1 697/4885 |
| US-20110082176-A1 | Stilbenes and Chalcones for the Prevention and Treatment of Cardiovascular Diseases | APOB, APOL1, HDLBP | CYP1A1 217/4885CYP1A2 808/4885CYP1B1 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.