Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PYGL | P06737 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797192 | 0.91 | ALDH1A1 (0.38) | ALDH1A1PYGLNQO2ABL1NPC1 | |
| SCHEMBL16095650 | 0.88 | ALDH1A1 (0.38) | ALDH1A1PYGLNQO2ABL1NPC1 | |
| SCHEMBL3333108 | 0.86 | ALDH1A1 (0.38) | ALDH1A1PYGLNQO2ABL1NPC1 | |
| SCHEMBL16127200 | 0.86 | ALDH1A1 (0.36) | ALDH1A1NQO2ABL1NPC1RAB9A | |
| SCHEMBL16036011 | 0.83 | ALDH1A1 (0.36) | ALDH1A1NQO2ABL1SMN1; SMN2KDM4E | |
| SCHEMBL29557036 | 0.83 | ALDH1A1 (0.36) | ALDH1A1NQO2ABL1SMN1; SMN2KDM4E | |
| SCHEMBL16047076 | 0.83 | NQO2 (0.38) | ALDH1A1NQO2ABL1NPC1RAB9A | |
| SCHEMBL16035807 | 0.83 | ALDH1A1 (0.36) | ALDH1A1NQO2ABL1NPC1RAB9A | |
| SCHEMBL16036003 | 0.83 | ALDH1A1 (0.36) | ALDH1A1NQO2NPC1KDM4ECYP1A2 | |
| SCHEMBL29556229 | 0.83 | ALDH1A1 (0.36) | ALDH1A1NQO2ABL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292502-A | Novel 4-aminopyridine and 6-aminopyrimidine carboxylates as herbicides | 美国陶氏益农公司 | 2021-08-24 | — | — | CN | disclosed |
| US-10765114-B2 | 4-amino-6-(pyridyl and 2-substitutedphenyl)-picolinates and 6-amino-2-(pyridyl and 2-substitutedphenyl)-pyrimidine-4-carboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2020-09-08 | — | — | US | disclosed |
| EP-2967057-B1 | NOVEL 4-AMINOPYRIDINE AND 6-AMINOPYRIMIDINE CARBOXYLATES AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2018-11-21 | — | — | EP | disclosed |
| EP-2967057-A1 | NOVEL 4-AMINOPYRIDINE AND 6-AMINOPYRIMIDINE CARBOXYLATES AS HERBICIDES | Dow AgroSciences LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014150809-A1 | NOVEL 4-AMINOPYRIDINE AND 6-AMINOPYRIMIDINE CARBOXYLATES AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140274703-A1 | NOVEL 4-AMINO-6-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PICOLINATES AND 6-AMINO-2-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10765114-B2 | 4-amino-6-(pyridyl and 2-substitutedphenyl)-picolinates and 6-amino-2-(pyridyl and 2-substitutedphenyl)-pyrimidine-4-carboxylates and their use as herbicides | DDT, P2RX6, PLPBP | ALDH1A1 951/4885PYGL 677/4885NQO2 434/4885 |
| US-20140274703-A1 | NOVEL 4-AMINO-6-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PICOLINATES AND 6-AMINO-2-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, PLPBP, P2RX6 | ALDH1A1 1043/4885PYGL 618/4885NQO2 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.