SCHEMBL16044787

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Trifluoroacetic Acid SCHEMBL18759481	0.92	PDE10A (0.41)	ADORA2BADORA2AGABRA1GABRG2GABRB3
	SCHEMBL16044407	0.88	GABRA1 (0.40)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL16044197	0.88	GABRA1 (0.38)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL16046796	0.86	GRM1 (0.44)	ADORA2BADORA2AGABRA1GABRG2GABRB3
	SCHEMBL16044266	0.86	MAPK14 (0.50)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL16046501	0.86	MAPK14 (0.50)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL16045669	0.84	CYP2A6 (0.38)	GABRA1GABRG2GABRB3GABRA3GABRA2
	Trifluoroacetic Acid SCHEMBL18759462	0.82	PDE10A (0.40)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL16045415	0.82	KMT2A (0.46)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL16045348	0.82	KMT2A (0.46)	GABRA1GABRG2GABRB3GABRA3GABRA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.