Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.50 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.50 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.50 |
| ▸ | GJA1 | P17302 | 1/20 | 0.49 |
| ▸ | GJB2 | P29033 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.48 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197649 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| Trehalose SCHEMBL12694649 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| SCHEMBL17154856 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| Trehalose SCHEMBL23029503 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| Trehalose SCHEMBL20111150 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| Trehalose SCHEMBL25304700 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| SCHEMBL20063941 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| Trehalose SCHEMBL732715 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| SCHEMBL5357747 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA | |
| Trehalose SCHEMBL4257808 | 0.98 | MEN1 (0.57) | MEN1KMT2APTPN1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107773780-A | A kind of poly- trehalose material and preparation method thereof | 南京禾文化创意有限公司 | 2018-03-09 | — | — | CN | claimed |
| CN-115386259-B | Dry-proof and freeze-proof photosensitive hydrogel ink, preparation method thereof, high-precision photo-curing hydrogel and application thereof | 中国科学院兰州化学物理研究所 | 2023-11-14 | — | — | CN | disclosed |
| CN-115386259-A | Anti-dry and anti-freezing photosensitive hydrogel ink, preparation method thereof, high-precision photocured hydrogel and application thereof | 中国科学院兰州化学物理研究所 | 2022-11-25 | — | — | CN | disclosed |
| US-10662295-B2 | Trehalose hydrogels for stabilization and delivery of proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-05-26 | — | — | US | disclosed |
| US-10662295-B2 | Trehalose hydrogels for stabilization and delivery of proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-05-26 | — | — | US | disclosed |
| EP-3180030-B1 | TREHALOSE HYDROGELS FOR STABILIZATION AND DELIVERY OF PROTEINS | UNIV CALIFORNIA (US) | 2019-10-09 | — | — | EP | disclosed |
| US-20190195883-A1 | DIAGNOSTIC SEQUENCING VIA TABLETS | CHAN WARREN CHE WOR (CA) | 2019-06-27 | — | — | US | disclosed |
| CN-107773780-A | A kind of poly- trehalose material and preparation method thereof | 南京禾文化创意有限公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-107773780-A | A kind of poly- trehalose material and preparation method thereof | 南京禾文化创意有限公司 | 2018-03-09 | — | — | CN | disclosed |
| US-20180015167-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2018-01-18 | — | — | US | disclosed |
| US-20170240711-A1 | TREHALOSE HYDROGELS FOR STABILIZATION AND DELIVERY OF PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-08-24 | — | — | US | disclosed |
| EP-3180030-A1 | TREHALOSE HYDROGELS FOR STABILIZATION AND DELIVERY OF PROTEINS | The Regents of The University of California (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016025551-A1 | TREHALOSE HYDROGELS FOR STABILIZATION AND DELIVERY OF PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-18 | — | — | WO | disclosed |
| WO-2014160377-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | INVIVO THERAPEUTICS CORPORATION (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140271601-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | INVIVO THERAPEUTICS CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015167-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | TREH, TBCA, BMP2 | MEN1 4382/4885KMT2A 3483/4885PTPN1 2960/4885 |
| US-20140271601-A1 | CROSSLINKABLE TREHALOSE FOR THE COVALENT INCORPORATION IN HYDROGELS AND METHODS OF USE | TREH, TBCA, BMP2 | MEN1 4382/4885KMT2A 3483/4885PTPN1 2960/4885 |
| US-20170240711-A1 | TREHALOSE HYDROGELS FOR STABILIZATION AND DELIVERY OF PROTEINS | TREH, TBCA, HSPA4 | MEN1 3418/4885KMT2A 4452/4885PTPN1 3837/4885 |
| US-10662295-B2 | Trehalose hydrogels for stabilization and delivery of proteins | TREH, TBCA, HSPA4 | MEN1 3418/4885KMT2A 4452/4885PTPN1 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.