Trehalose

Trehalose

SCHEMBL732715

OCC1O[C@@H](O[C@H]2OC(CO)[C@@H](O)[C@@H](O)C2O)C(O)C(O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ PTPN1 P18031 2/20 0.56
▸ L3MBTL1 Q9Y468 2/20 0.55
▸ GAA P10253 1/20 0.53
▸ TYR P14679 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ LGALS8 O00214 2/20 0.51
▸ LGALS3 P17931 2/20 0.51
▸ LGALS4 P56470 1/20 0.51
▸ LGALS9 O00182 1/20 0.50
▸ LGALS1 P09382 1/20 0.50
▸ GJA1 P17302 1/20 0.50
▸ GJB2 P29033 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ TSHR P16473 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18197649 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL4257808 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL12694649 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
SCHEMBL17154856 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL25304700 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL20111150 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL23029503 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
SCHEMBL20063941 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
SCHEMBL5357747 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
SCHEMBL5081689 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791069-B1 Pharmaceutical composition of nanoparticles GP MEDICAL, INC. (US) 2014-07-29 — — US disclosed
US-8663599-B1 Pharmaceutical composition of nanoparticles GP MEDICAL, INC. (US) 2014-03-04 — — US disclosed
US-8461316-B1 Nanoparticles for delivery of bioactive agents GP MEDICAL, INC. (US) 2013-06-11 — — US disclosed
US-8337811-B1 Pharmaceutical composition of nanoparticles GP MEDICAL, INC. (US) 2012-12-25 — — US disclosed
US-8318200-B1 Pharmaceutical composition of nanoparticles GP MEDICAL, INC. (US) 2012-11-27 — — US disclosed
US-8287905-B1 Pharmaceutical composition of nanoparticles GP MEDICAL, INC. (US) 2012-10-16 — — US disclosed
US-20120258176-A1 NANOPARTICLES FOR PROTEIN DRUG DELIVERY NANOMEGA MEDICAL CORPORATION 2012-10-11 — — US disclosed
US-8283317-B1 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2012-10-09 — — US disclosed
US-8257740-B1 Pharmaceutical composition of nanoparticles GP MEDICAL, INC. (US) 2012-09-04 — — US disclosed
US-20120207845-A1 PHARMACEUTICAL COMPOSITION OF NANOPARTICLES NANOMEGA MEDICAL CORPORATION 2012-08-16 — — US disclosed
US-7863258-B1 positively charged chitosan shell, polyglutamic acid core, negative surface charge; enhanced permeability for paracellular drug delivery; pemetrexed; gemcitabine GP MEDICAL, INC. (US) 2011-01-04 — — US disclosed
US-7858596-B2 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2010-12-28 — — US disclosed
US-7611690-B2 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2009-11-03 — — US disclosed
US-7604795-B1 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2009-10-20 — — US disclosed
US-20090202628-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2009-08-13 — — US disclosed
US-7556826-B2 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2009-07-07 — — US disclosed
US-20090155374-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2009-06-18 — — US disclosed
US-20090142405-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2009-06-04 — — US disclosed
US-7541046-B1 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2009-06-02 — — US disclosed
US-20090004266-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2009-01-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120207845-A1 PHARMACEUTICAL COMPOSITION OF NANOPARTICLES DSP, EPCAM, JUP MEN1 925/4885KMT2A 3550/4885PTPN1 875/4885
US-20120258176-A1 NANOPARTICLES FOR PROTEIN DRUG DELIVERY PELP1, ARGLU1, ACP1 MEN1 2726/4885KMT2A 3305/4885PTPN1 2096/4885
US-20090142405-A1 Nanoparticles for protein drug delivery SLC47A1, LNPEP, SLC1A5 MEN1 3843/4885KMT2A 4186/4885PTPN1 3366/4885
US-20090004266-A1 Nanoparticles for protein drug delivery PELP1, FABP2, BMP6 MEN1 3731/4885KMT2A 4091/4885PTPN1 3880/4885
US-20090202628-A1 Nanoparticles for protein drug delivery SLC47A1, LNPEP, SLC1A5 MEN1 3843/4885KMT2A 4186/4885PTPN1 3366/4885
US-20090155374-A1 Nanoparticles for protein drug delivery SLC47A1, LNPEP, SLC1A5 MEN1 3843/4885KMT2A 4186/4885PTPN1 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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