SCHEMBL16045786

SCHEMBL16045786

CC(C)CC(OS(=O)(=O)c1ccccc1)C(C)C(C)OC(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
LARS1 Q9P2J5 1/20 0.39
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
NPC1 O15118 3/20 0.37
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
POLB P06746 1/20 0.36
SCN1A P35498 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
PRKCA P17252 1/20 0.34
CA12 O43570 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16045785 0.90 RAB9A (0.40) RAB9ATSHRTP53LARS1PDCD1
SCHEMBL1785964 0.85 TSHR (0.46) RAB9ATSHRTP53PDCD1CD274
SCHEMBL16047796 0.84 MAPK1 (0.37) RAB9ATSHRTP53PDCD1CD274
SCHEMBL16048035 0.84 TSHR (0.45) RAB9ATSHRTP53PDCD1CD274
SCHEMBL16046081 0.83 LARS1 (0.39) RAB9ALARS1LMNASMN1; SMN2ALDH1A1
SCHEMBL16047777 0.83 TSHR (0.41) RAB9ATSHRTP53PDCD1CD274
SCHEMBL16046812 0.82 LMNA (0.40) RAB9ATSHRTP53PDCD1CD274
SCHEMBL16044141 0.82 TSHR (0.41) RAB9ATSHRTP53PDCD1CD274
SCHEMBL16046260 0.81 LMNA (0.39) RAB9ATSHRTP53PDCD1CD274
SCHEMBL16046262 0.81 LMNA (0.39) RAB9ATSHRTP53PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN claimed
EP-2969201-B1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2022-05-04 EP disclosed
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN disclosed
CN-109180843-A The non-phthalic acid ester compound as electron donor for polyolefin catalyst 美国台塑公司 2019-01-11 CN disclosed
CN-105339085-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2018-06-26 CN disclosed
US-9790291-B2 Non-phthalate compounds as electron donors for polyolefin catalysts FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-17 US disclosed
EP-2969201-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS Formosa Plastics Corporation, U.S.A. (US) 2016-01-20 EP disclosed
WO-2014160012-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-10-02 WO disclosed
US-20140275456-A1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-09-18 US disclosed