Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402622 | 0.89 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16049321 | 0.84 | SLC7A5 (0.58) | SLC1A3SLC1A2SLC7A5SLC1A1 | |
| SCHEMBL29610258 | 0.84 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23408823 | 0.82 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Leucine SCHEMBL10776473 | 0.81 | SLC7A5 (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Glutamic Acid SCHEMBL10776478 | 0.81 | SLC1A1 (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| D-Glutamate SCHEMBL3512077 | 0.79 | SLC1A3 (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Glutamic Acid SCHEMBL5614072 | 0.79 | SLC1A3 (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Glutamic Acid SCHEMBL1126187 | 0.79 | SLC1A3 (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Glutamic Acid SCHEMBL24357 | 0.79 | SLC1A3 (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49816-E1 | Dipeptides as inhibitors of human immunoproteasomes | CORNELL UNIVERSITY (US) | 2024-01-30 | — | — | US | disclosed |
| EP-4229075-A1 | GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS | The Regents of the University of California (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081631-A1 | GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |