Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16053273 | 0.78 | PLD1 (0.39) | MAPTRAB9ADRD4LATS1CYP2D6 | |
| SCHEMBL20586173 | 0.78 | DRD4 (0.37) | MAPTRAB9ADRD4BCHEACHE | |
| SCHEMBL20993537 | 0.73 | HTR3A (0.41) | HTR3ADRD4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL20993629 | 0.73 | HTR3A (0.41) | HTR3ADRD4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL24352612 | 0.73 | HTR3A (0.41) | HTR3ADRD4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL9984343 | 0.72 | HTR2A (0.39) | MAPTCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31232802 | 0.70 | PLD1 (0.42) | MAPTRAB9AHTR2AHTR2CHTR2B | |
| SCHEMBL12807031 | 0.70 | SLC6A2 (0.49) | HTR3AMAPTCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL16053274 | 0.69 | MAPT (0.76) | HTR3AMAPTRAB9ADRD4BCHE | |
| SCHEMBL6110760 | 0.69 | HTR2C (0.38) | MAPTCYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970260-A1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | Proximagen Limited (GB) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014140592-A1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LIMITED (GB) | 2014-09-18 | — | — | WO | disclosed |