Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900748 | 0.75 | PLD1 (0.42) | HTR2CHTR2BHTR2APLD1SIGMAR1 | |
| SCHEMBL31232802 | 0.75 | PLD1 (0.42) | HTR2CHTR2BHTR2APLD1SIGMAR1 | |
| SCHEMBL9984343 | 0.74 | HTR2A (0.39) | HTR2CHTR2BHTR2APLD1SIGMAR1 | |
| SCHEMBL12807031 | 0.74 | SLC6A2 (0.49) | HTR2CHTR2BHTR2APLD1SIGMAR1 | |
| SCHEMBL24352612 | 0.73 | HTR3A (0.41) | HTR2CHTR2BHTR2APLD1HTR7 | |
| SCHEMBL27911852 | 0.73 | HTT (0.47) | HTR2CHTR2BHTR2ASIGMAR1ALDH1A1 | |
| SCHEMBL20993629 | 0.73 | HTR3A (0.41) | HTR2CHTR2BHTR2APLD1HTR7 | |
| SCHEMBL20993537 | 0.73 | HTR3A (0.41) | HTR2CHTR2BHTR2APLD1HTR7 | |
| SCHEMBL16500313 | 0.72 | ADRB1 (0.46) | HTR2CHTR2BHTR2AHTR7ALDH1A1 | |
| SCHEMBL7400894 | 0.71 | PLD1 (0.40) | HTR2CHTR2BHTR2APLD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006035283-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-06 | — | — | WO | disclosed |