Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16054505 | 0.87 | AKR1B1 (0.42) | GAATAAR1KMT2AMAPTALDH1A1 | |
| SCHEMBL10058270 | 0.87 | GAA (0.37) | GAATAAR1BACE1KDM4EHTT | |
| SCHEMBL10325433 | 0.87 | AKR1B1 (0.42) | GAATAAR1KMT2AMAPTALDH1A1 | |
| SCHEMBL2428955 | 0.80 | GAA (0.53) | GAATAAR1BACE1KDM4EHTT | |
| SCHEMBL697704 | 0.77 | TAAR1 (0.67) | GAATAAR1BACE1KDM4EHTT | |
| SCHEMBL6883141 | 0.76 | TAAR1 (0.55) | GAATAAR1BACE1KDM4EHTT | |
| SCHEMBL3265635 | 0.73 | TAAR1 (0.68) | GAATAAR1BACE1KDM4EHTT | |
| SCHEMBL2222710 | 0.73 | TAAR1 (0.56) | GAATAAR1BACE1HTTATM | |
| SCHEMBL6201835 | 0.72 | THRB (0.36) | GAATAAR1BACE1KDM4EALDH1A1 | |
| SCHEMBL11454449 | 0.72 | TAAR1 (0.47) | GAATAAR1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968211-A1 | PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014142519-A1 | PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | disclosed |