SCHEMBL697704

SCHEMBL697704

OCc1c(F)cccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.67
GAA P10253 1/20 0.62
BACE1 P56817 1/20 0.53
KDM4E B2RXH2 2/20 0.51
HTT P42858 2/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 1/20 0.49
CYP2A13 Q16696 1/20 0.47
CNR1 P21554 1/20 0.46
TP53 P04637 2/20 0.46
DAO P14920 1/20 0.46
ATM Q13315 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3265635 0.87 TAAR1 (0.68) TAAR1GAABACE1KDM4EHTT
SCHEMBL2199784 0.84 TAAR1 (0.63) TAAR1GAABACE1KDM4EHTT
SCHEMBL110369 0.83 AKR1B1 (0.52) TAAR1GAAHTTMAPTKMT2A
SCHEMBL113326 0.83 TAAR1 (0.48) TAAR1GAABACE1KDM4EMAPT
SCHEMBL3455236 0.80 TAAR1 (0.77) TAAR1GAABACE1KDM4EHTT
SCHEMBL3115865 0.80 TAAR1 (0.70) TAAR1GAABACE1KDM4EHTT
SCHEMBL1197584 0.80 TAAR1 (1.00) TAAR1GAABACE1KDM4EHTT
SCHEMBL30776827 0.79 TAAR1 (0.63) TAAR1GAABACE1KDM4EHTT
SCHEMBL28596017 0.79 TAAR1 (0.63) TAAR1GAABACE1KDM4EHTT
SCHEMBL601569 0.79 TAAR1 (0.63) TAAR1GAABACE1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962674-B2 Curcumin derivative TOKYO INSTITUTE OF TECHNOLOGY (JP) 2015-02-24 US claimed
US-20100048901-A1 NOVEL CURCUMIN DERIVATIVE TOKYO INSTITUTE OF TECHNOLOGY (JP) 2010-02-25 US claimed
EP-2123637-A1 NOVEL CURCUMIN DERIVATIVE Tokyo Institute of Technology (JP) 2009-11-25 EP claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-0979812-B1 Process for the preparation of fluorinated benzyl alcools and benzyl aldehydes BAYER AG (DE) 2003-10-29 EP claimed
EP-0979812-A1 Process for the preparation of fluorinated benzyl alcools and benzyl aldehydes Bayer Aktiengesellschaft (DE) 2000-02-16 EP claimed
US-5922117-A Ink compositions containing alcohols XEROX CORPORATION (US) 1999-07-13 US claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed
CN-119972172-A Heterogeneous organic polymer catalyst, preparation method thereof and method for synthesizing aldehyde or lactone compound 武汉光化学技术研究院 2025-05-13 CN disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
CN-110770214-B Heterocyclic P2X7 antagonists 布雷耶疗法有限公司 2024-03-29 CN disclosed
US-20230295087-A1 AGONISTS OF ROR GAMMAt BRISTOL MYERS SQUIBB CO (US) 2023-09-21 US disclosed
EP-0057795-B1 HALOBENZYL ESTERS OF HALOALKENYLCYCLOPROPANE ACIDS, THEIR PREPARATION, COMPOSITIONS AND METHOD OF COMBATING INSECT PESTS THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-07-10 EP disclosed
EP-0126875-A1 Light-sensitive polycondensation product with diazonium groups, process for the preparation thereof and light-sensitive registration material which contains this polycondensation product HOECHST AKTIENGESELLSCHAFT (DE) 1984-12-05 EP disclosed
EP-0093010-A2 Alpha-hydroxyethylphosphinates, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-02 EP disclosed
EP-0060617-A1 Fluorobenzyl cyclopropane carboxylates, their preparation, compositions and use as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-22 EP disclosed
EP-0057795-A1 Halobenzyl esters of haloalkenylcyclopropane acids, their preparation, compositions and method of combating insect pests therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048901-A1 NOVEL CURCUMIN DERIVATIVE BACE1, APP, BACE2 TAAR1 789/4885GAA 2715/4885BACE1 1/4885
US-20230295087-A1 AGONISTS OF ROR GAMMAt RORB, RORA, RORC TAAR1 458/4885GAA 1445/4885BACE1 1910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.