Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16057232 | 0.90 | HTT (0.42) | HTTL3MBTL1NPSR1KMT2AKDM4E | |
| SCHEMBL16057907 | 0.86 | SLC13A5 (0.41) | HTTL3MBTL1NPSR1KMT2AKDM4E | |
| SCHEMBL17557052 | 0.84 | KMT2A (0.47) | HTTL3MBTL1NPSR1KMT2AMEN1 | |
| SCHEMBL16058683 | 0.84 | PAX8 (0.42) | HTTL3MBTL1RAB9ASLC13A5 | |
| SCHEMBL16056979 | 0.83 | FFAR4 (0.43) | — | |
| SCHEMBL16057028 | 0.82 | FFAR1 (0.45) | HTTL3MBTL1NPSR1KMT2AALDH1A1 | |
| SCHEMBL16057945 | 0.81 | L3MBTL1 (0.42) | HTTL3MBTL1RAB9AALDH1A1HPGD | |
| SCHEMBL14975892 | 0.81 | MEN1 (0.42) | HTTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL16057659 | 0.81 | PPARG (0.40) | — | |
| SCHEMBL28736458 | 0.81 | SLC13A5 (0.45) | L3MBTL1KMT2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144836-A2 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-18 | — | — | WO | disclosed |