Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16057233 | 0.90 | HTT (0.41) | HTTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL16057903 | 0.85 | NOTUM (0.41) | HTTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL17557050 | 0.84 | KMT2A (0.48) | HTTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL16056978 | 0.83 | MGLL (0.43) | HTTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL16058681 | 0.82 | PAX8 (0.42) | HTTL3MBTL1LMNARAB9A | |
| SCHEMBL16057027 | 0.82 | FFAR1 (0.43) | HTTKMT2ANPSR1L3MBTL1MEN1 | |
| SCHEMBL16057944 | 0.81 | L3MBTL1 (0.41) | HTTL3MBTL1LMNANPC1RAB9A | |
| SCHEMBL1597855 | 0.80 | NOS3 (0.42) | HTTKMT2ANPSR1L3MBTL1KDM4E | |
| SCHEMBL16057657 | 0.80 | PPARG (0.40) | WNT3A | |
| SCHEMBL14975891 | 0.79 | MEN1 (0.42) | HTTKMT2AMEN1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144836-A2 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-18 | — | — | WO | disclosed |