Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.66 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.63 |
| ▸ | PRKACA | P17612 | 2/20 | 0.62 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.61 |
| ▸ | SRC | P12931 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.61 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.61 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | FBP1 | P09467 | 1/20 | 0.61 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.61 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16056094 | 0.93 | MARS1 (0.66) | MARS1PLA2G2APRKACAP2RY1P2RY2 | |
| SCHEMBL6408983 | 0.88 | MARS1 (0.80) | MARS1PRKACAP2RY1P2RY2ADORA1 | |
| SCHEMBL6408975 | 0.88 | MARS1 (0.80) | MARS1PRKACAP2RY1P2RY2ADORA1 | |
| SCHEMBL6704430 | 0.84 | PRKACA (0.75) | MARS1PLA2G2APRKACAP2RY1P2RY2 | |
| SCHEMBL2761284 | 0.84 | MARS1 (0.74) | MARS1PLA2G2APRKACAP2RY1P2RY2 | |
| SCHEMBL8846496 | 0.83 | MARS1 (0.73) | MARS1PLA2G2APRKACAP2RY1P2RY2 | |
| SCHEMBL1757017 | 0.83 | ADORA1 (0.73) | MARS1PLA2G2APRKACAP2RY1P2RY2 | |
| SCHEMBL9426538 | 0.83 | PRKACA (0.73) | MARS1PRKACAP2RY1P2RY2ADORA1 | |
| SCHEMBL2463542 | 0.83 | PRKACA (0.73) | MARS1PRKACAP2RY1P2RY2ADORA1 | |
| SCHEMBL19859780 | 0.83 | ADORA1 (0.73) | MARS1PLA2G2APRKACAP2RY1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116511-A1 | COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF | Alltech, Inc. (US) | 2017-01-18 | — | — | EP | disclosed |
| EP-2968404-A1 | COMPOSITIONS COMPRISING SELENIUM AND USE OF SAME FOR THE TREATMENT AND PREVENTION OF DISEASE OR CONDITIONS ASSOCIATED WITH MITOCHONDRIAL DYSFUNCTION | Alltech, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2015137983-A1 | COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF | ALLTECH, INC. (US) | 2015-09-17 | — | — | WO | disclosed |
| WO-2014144776-A1 | COMPOSITIONS COMPRISING SELENIUM AND USE OF SAME FOR THE TREATMENT AND PREVENTION OF DISEASE OR CONDITIONS ASSOCIATED WITH MITOCHONDRIAL DYSFUNCTION | ALLTECH, INC. (US) | 2014-09-18 | — | — | WO | disclosed |