SCHEMBL6408983

SCHEMBL6408983

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COC(=O)[C@H](N)CCS)C(O)C1O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MARS1 P56192 1/20 0.80
NNMT P40261 3/20 0.66
DOT1L Q8TEK3 5/20 0.65
EHMT2 Q96KQ7 4/20 0.65
NSD2 O96028 3/20 0.65
SETD7 Q8WTS6 3/20 0.65
CARM1 Q86X55 3/20 0.65
PCMT1 P22061 2/20 0.65
TRDMT1 O14717 2/20 0.65
PRMT5 O14744 2/20 0.65
INMT O95050 2/20 0.65
METTL3 Q86U44 2/20 0.65
PRMT1 Q99873 2/20 0.65
EHMT1 Q9H9B1 2/20 0.65
METTL14 Q9HCE5 2/20 0.65
RNMT O43148 1/20 0.65
TPMT P51580 1/20 0.65
NSD1 Q96L73 1/20 0.65
SETD2 Q9BYW2 1/20 0.65
NSD3 Q9BZ95 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6408975 1.00 MARS1 (0.80) MARS1NNMTDOT1LEHMT2NSD2
SCHEMBL16056991 0.93 MARS1 (0.70) MARS1NNMTDOT1LEHMT2NSD2
SCHEMBL3014292 0.89 MARS1 (1.00) MARS1NNMTDOT1LEHMT2NSD2
SCHEMBL583457 0.89 MARS1 (1.00) MARS1NNMTDOT1LEHMT2NSD2
SCHEMBL1858296 0.89 MARS1 (0.75) MARS1NNMTDOT1LEHMT2NSD2
SCHEMBL16057443 0.88 MARS1 (0.66) MARS1ADORA1DNPH1PRKAB2TRPM2
SCHEMBL16056094 0.88 MARS1 (0.66) MARS1ADORA1DNPH1PRKAB2TRPM2
SCHEMBL2761284 0.86 MARS1 (0.74) MARS1DOT1LADORA1DNPH1PRKAB2
Sulfuric Acid SCHEMBL28535358 0.86 MARS1 (0.93) MARS1NNMTDOT1LEHMT2NSD2
Adenosine SCHEMBL6408967 0.86 NNMT (0.76) NNMTDOT1LEHMT2NSD2SETD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478844-A Recombinant strain for synthesizing sakura extract, construction method thereof, and method for synthesizing sakura extract by fermentation and application 南京师范大学 2023-07-25 CN claimed
WO-2020225946-A1 METHOD FOR EVALUATING SAMPLE, ANALYSIS METHOD, METHOD FOR DETECTING DEGRADED SAMPLE, MARKER FOR DETECTING DEGRADED BLOOD PLASMA SAMPLE, AND MARKER FOR DETECTING DEGRADED SERUM SAMPLE 株式会社島津製作所 2020-11-12 WO claimed
CN-118086420-A Synthesis method of ergothioneine 珠海宝锐生物科技有限公司 2024-05-28 CN disclosed
CN-117957234-A Thienopyrrole compounds 吉利德科学公司 2024-04-30 CN disclosed
CN-117741120-A Reagent card for quantitatively detecting homocysteine 江苏扬新生物医药有限公司 2024-03-22 CN disclosed
CN-117004544-B Genetically engineered bacterium for synthesizing vanillin from head by taking glucose as substrate and application thereof 北京化工大学 2023-12-12 CN disclosed
CN-117106062-A S-adenosyl homocysteine conjugate and monoclonal antibody preparation and application 南京拂晓生物科技有限公司 2023-11-24 CN disclosed
CN-117120450-A Thienopyrrole compounds 吉利德科学公司 2023-11-24 CN disclosed
CN-117004544-A Genetically engineered bacterium for synthesizing vanillin from head by taking glucose as substrate and application thereof 北京化工大学 2023-11-07 CN disclosed
CN-116783202-A Thienopyrrole compounds 吉利德科学公司 2023-09-19 CN disclosed
CN-116529258-A Interleukin-2-Fc fusion proteins and methods of use 吉利德科学公司 2023-08-01 CN disclosed
CN-101246177-A Homo-type cysteine immunity colloidal gold detecting test paper and method for producing the same BEIJING HAFO BIOMEDICAL RES CT (CN) 2008-08-20 CN disclosed
CN-101157929-A Safraninemycin biological synthesis gene cluster SHANGHAI INST ORGANIC CHEM (CN) 2008-04-09 CN disclosed
CN-1303219-C Method of screening out model for preparing hydrolase inhibitor of adenosine homocysteine CHANGCHUN APPLIED CHEMISTRY (CN) 2007-03-07 CN disclosed
CN-1687449-A Method of screening out model for preparing hydrolase inhibitor of adenosine homocysteine CHANGCHUN APPLIED CHEMISTRY (CN) 2005-10-26 CN disclosed
CN-1687449-A Method of screening out model for preparing hydrolase inhibitor of adenosine homocysteine CHANGCHUN APPLIED CHEMISTRY (CN) 2005-10-26 CN disclosed
US-20050044582-A1 Novel polynucleotides and uses therefor THE CORPORATION OF THE TRUSTEES OF THE ORDER OF THE SISTERS OF MERCY IN QUEENSLAND 2005-02-24 US disclosed
WO-2003055997-A1 GENOMIC SEQUENCES ENCODING DENDRITIC CELL EXPRESSED S-ADENOSYL HOMOCYSTEINE HYDROLASE LIKE MOLECULES THE CORPORATION OF THE TRUSTEES OF THE ORDER OF THE SISTERS OF MERCY IN QUEENSLAND (AU) 2003-07-10 WO disclosed
US-5872104-A BACTERICIDES AND RESISTANT BACTERIA WITH METHYLATION INHIBITORS ORIDIGM CORPORATION (US) 1999-02-16 US disclosed
WO-1996020010-A1 COMBINATION FOR REDUCING ANTIMICROBIAL RESISTANCE USING A METHYLATION INHIBITOR IN COMBINATION WITH AN ANTIBIOTIC ORIDIGM CORPORATION (US) 1996-07-04 WO disclosed