Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 2/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18562084 | 0.89 | KMT2A (0.37) | ALDH1A1LMNAMAPTTSHRMEN1 | |
| SCHEMBL23928227 | 0.89 | TAAR1 (0.48) | ALDH1A1TSHRNFKB1AOC3KMT2A | |
| SCHEMBL20207410 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL5789378 | 0.81 | LTA4H (0.48) | CALM1ALDH1A1LMNACYP2D6TSHR | |
| SCHEMBL7794555 | 0.81 | CYP2C19 (0.44) | ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL23928216 | 0.81 | AOC3 (0.48) | ESRRGALDH1A1LMNATSHRAOC3 | |
| SCHEMBL23928110 | 0.79 | ESRRG (0.52) | ESRRGALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3956323 | 0.79 | MEN1 (0.33) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL22082130 | 0.79 | APP (0.37) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL10485681 | 0.79 | USP8 (0.37) | ALDH1A1LMNAMAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970098-A1 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS | Pharmatrophix Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144342-A1 | NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS | PHARMATROPHIX, INC. (US) | 2014-09-18 | — | — | WO | disclosed |