Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15719924 | 0.92 | TSHR (0.36) | APEX1BLML3MBTL1TSHRBCHE | |
| SCHEMBL15719878 | 0.75 | TSHR (0.39) | L3MBTL1TSHR | |
| SCHEMBL6869169 | 0.75 | BRD4 (0.50) | L3MBTL1POLB | |
| SCHEMBL16058256 | 0.73 | L3MBTL1 (0.36) | APEX1BLML3MBTL1BCHE | |
| SCHEMBL2334268 | 0.73 | TSHR (0.32) | APEX1BLML3MBTL1TSHRPOLB | |
| SCHEMBL6865080 | 0.72 | KMT2A (0.40) | L3MBTL1TSHRPOLB | |
| SCHEMBL17474301 | 0.72 | APEX1 (0.34) | APEX1BLML3MBTL1TSHR | |
| SCHEMBL16059034 | 0.71 | PRMT5 (0.47) | TSHR | |
| SCHEMBL2331981 | 0.70 | TSHR (0.36) | APEX1BLML3MBTL1TSHRBCHE | |
| SCHEMBL2524010 | 0.70 | POLB (0.54) | APEX1BLML3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968257-A1 | METHODS AND COMPOSITONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144546-A1 | METHODS AND COMPOSITONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |