Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PLD3 | Q8IV08 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BRAF | P15056 | 2/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376394 | 0.89 | BRAF (0.54) | LMNAALDH1A1GAAMAOAMAOB | |
| SCHEMBL16029365 | 0.86 | MAOA (0.63) | LMNAALDH1A1GAAMAOAMAOB | |
| SCHEMBL16079502 | 0.86 | MAOB (0.63) | LMNAALDH1A1GAAMAOAMAOB | |
| SCHEMBL17772706 | 0.85 | MAOA (0.74) | LMNAALDH1A1GAAMAOAMAOB | |
| SCHEMBL16030391 | 0.84 | MAOA (0.61) | LMNAALDH1A1GAAMAOAMAOB | |
| SCHEMBL16029594 | 0.83 | MAOA (0.60) | LMNAALDH1A1GAAMAOAMAOB | |
| SCHEMBL16029599 | 0.83 | MAOB (0.63) | LMNAALDH1A1GAAMAOAMAOB | |
| SCHEMBL16079496 | 0.82 | LMNA (0.68) | LMNAALDH1A1GAAMAOAMAOB | |
| SCHEMBL16122851 | 0.82 | MAPT (0.63) | LMNAALDH1A1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL16079488 | 0.81 | MAOB (0.62) | LMNAALDH1A1GAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968257-A1 | METHODS AND COMPOSITONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2968220-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | Agenebio, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144546-A1 | METHODS AND COMPOSITONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014144801-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | AGENEBIO INC. (US) | 2014-09-18 | — | — | WO | disclosed |