SCHEMBL16059482

SCHEMBL16059482

NC(=O)c1cccnc1-c1ccncc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.50
KDM4E B2RXH2 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
CHUK O15111 2/20 0.47
PLK4 O00444 1/20 0.47
MAPK13 O15264 1/20 0.47
DYRK3 O43781 1/20 0.47
ROCK2 O75116 1/20 0.47
RPS6KA5 O75582 1/20 0.47
PRKD3 O94806 1/20 0.47
MAP4K4 O95819 1/20 0.47
CHEK2 O96017 1/20 0.47
PIM1 P11309 1/20 0.47
PHKG2 P15735 1/20 0.47
PRKACA P17612 1/20 0.47
RPS6KB1 P23443 1/20 0.47
CSNK1D P48730 1/20 0.47
CLK2 P49760 1/20 0.47
GSK3A P49840 1/20 0.47
PRKX P51817 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31660092 1.00 PARP1 (0.50) PARP1KDM4ETDP1CHUKPLK4
SCHEMBL29916420 0.87 KDM4E (0.55) PARP1KDM4ETDP1CLK4RAB9A
SCHEMBL945856 0.87 KDM4E (0.55) PARP1KDM4ETDP1CLK4RAB9A
SCHEMBL27967469 0.85 KDM4E (0.52) KDM4ETDP1CYP46A1CYP3A4CYP2C8
SCHEMBL4186883 0.85 KDM4E (0.65) PARP1KDM4ETDP1RAB9ACYP3A4
SCHEMBL30108233 0.84 PARP1 (0.49) PARP1KDM4ETDP1CHUKMKNK2
SCHEMBL6906432 0.84 KDM4E (0.71) KDM4ETDP1CYP46A1CYP3A4CYP2C8
SCHEMBL29453799 0.84 KDM4E (0.71) KDM4ETDP1CYP46A1CYP3A4CYP2C8
SCHEMBL1571384 0.83 MKNK1 (0.55) PARP1KDM4ETDP1PKN1PKN2
SCHEMBL29575496 0.83 MKNK1 (0.55) PARP1KDM4ETDP1PKN1PKN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028685-A1 Saliva Stabilization Solution For Use In Nucleic Acid Amplification Reactions And Methods Of Use For The Detection Of Pathogen Nucleic Acids UNIV COLORADO REGENTS (US) 2026-01-29 US claimed
WO-2021236696-A1 SALIVA STABILIZATION SOLUTION FOR USE IN NUCLEIC ACID AMPLIFICATION REACTIONS AND METHODS OF USE FOR THE DETECTION OF PATHOGEN NUCLEIC ACIDS THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) 2021-11-25 WO claimed
CN-104086482-B Chemical molecules inhibiting the splicing mechanism for the treatment of diseases caused by splicing abnormalities 国家科研中心 2017-10-13 CN claimed
US-12590955-B2 Methods and systems for processing particles ZEON CORPORATION (JP) 2026-03-31 US disclosed
US-20260071299-A1 APPARATUS AND METHODS FOR RARE EARTH ELEMENT RECOVERY AND PURIFICATION BATTELLE MEMORIAL INSTITUTE (US) 2026-03-12 US disclosed
US-20250381163-A1 Chelating Agents for Use in Cancer Therapy PLECO THERAPEUTICS B V (NL) 2025-12-18 US disclosed
US-12436081-B2 Methods and devices for multi-step cell purification and concentration ZEON CORPORTION (JP) 2025-10-07 US disclosed
WO-2025089964-A1 METHODS FOR TESTING ACTIVE COMPOUNDS IN MODELS WITH ELEVATED HEAVY METAL ACCUMULATION PLECO THERAPEUTICS B.V. (NL) 2025-05-01 WO disclosed
US-12258535-B2 Emulsions having oil phase surfactants and water phase additive blends PILOT CHEMICAL CORP. (US) 2025-03-25 US disclosed
CN-119630394-A Chelating agents for cancer treatment 普雷高治疗有限公司 2025-03-14 CN disclosed
US-20240368734-A1 METHODS FOR EXTRACTING RARE EARTH ELEMENTS FROM RARE EARTH ELEMENT SOURCES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2024-11-07 US disclosed
EP-2971279-A2 METHODS AND DEVICES FOR HIGH THROUGHPOUT PURIFICATION The Trustees of Princeton University (US) 2016-01-20 EP disclosed
EP-2971238-A1 METAL COMPLEXING AGENTS AS CORROSION INHIBITORS PRC-Desoto International, Inc. (US) 2016-01-20 EP disclosed
EP-2971287-A2 ON-CHIP MICROFLUIDIC PROCESSING OF PARTICLES GPB Scientific, LLC (US) 2016-01-20 EP disclosed
CN-105247102-A Metal complexes as corrosion inhibitors PRC DESOTO INT INC 2016-01-13 CN disclosed
CN-105247042-A Method and apparatus for high throughput purification UNIV PRINCETON 2016-01-13 CN disclosed
WO-2014145075-A9 METHODS AND DEVICES FOR HIGH THROUGHPOUT PURIFICATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2014-12-18 WO disclosed
WO-2014151491-A1 METAL COMPLEXING AGENTS AS CORROSION INHIBITORS PRC-DESOTO INTERNATIONAL, INC. (US) 2014-09-25 WO disclosed
WO-2014145075-A2 METHODS AND DEVICES FOR HIGH THROUGHPOUT PURIFICATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2014-09-18 WO disclosed
WO-2014145152-A2 ON-CHIP MICROFLUIDIC PROCESSING OF PARTICLES GPB SCIENTIFIC, LLC (US) 2014-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071299-A1 APPARATUS AND METHODS FOR RARE EARTH ELEMENT RECOVERY AND PURIFICATION ERCC4, ERCC2, XPA PARP1 3196/4885KDM4E 3353/4885TDP1 1749/4885
US-20260028685-A1 Saliva Stabilization Solution For Use In Nucleic Acid Amplification Reactions And Methods Of Use For The Detection Of Pathogen Nucleic Acids RNASEH1, ACE2, DDX42 PARP1 839/4885KDM4E 3634/4885TDP1 256/4885
US-12590955-B2 Methods and systems for processing particles EZR, CD47, CD44 PARP1 2784/4885KDM4E 4343/4885TDP1 4222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.