Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 3/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945856 | 1.00 | KDM4E (0.55) | KDM4ETDP1BCAT2PARP1NAPRT | |
| SCHEMBL16059482 | 0.87 | PARP1 (0.50) | KDM4ETDP1PARP1CLK4ALDH1A1 | |
| SCHEMBL31660092 | 0.87 | PARP1 (0.50) | KDM4ETDP1PARP1CLK4ALDH1A1 | |
| SCHEMBL15548944 | 0.86 | BCAT2 (0.61) | KDM4ETDP1BCAT2PARP1NAPRT | |
| SCHEMBL4186883 | 0.86 | KDM4E (0.65) | KDM4ETDP1PARP1NAPRTMAPT | |
| SCHEMBL12592293 | 0.86 | PLA2G2A (0.50) | KDM4ETDP1PARP1CLK4ALDH1A1 | |
| SCHEMBL21807964 | 0.86 | RAB9A (0.52) | KDM4ETDP1ALDH1A1RAB9A | |
| SCHEMBL30108238 | 0.86 | RAB9A (0.52) | KDM4ETDP1ALDH1A1RAB9A | |
| SCHEMBL30108233 | 0.86 | PARP1 (0.49) | KDM4ETDP1PARP1NAPRTMAPT | |
| SCHEMBL10969548 | 0.85 | RORB (0.60) | KDM4ETDP1NAPRTRORBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655618-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-107108534-B | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-05-09 | — | — | CN | disclosed |