Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 8/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148006 | 0.87 | CYP2D6 (0.42) | CNR1CNR2FAAHMEN1KMT2A | |
| SCHEMBL4971014 | 0.87 | POLB (0.39) | CNR1CNR2FAAHMEN1KMT2A | |
| SCHEMBL14016308 | 0.87 | MEN1 (0.48) | MEN1KMT2ATDP1POLBKDM4E | |
| SCHEMBL23135475 | 0.84 | CNR2 (0.47) | CNR1CNR2FAAHMEN1KMT2A | |
| SCHEMBL22168412 | 0.84 | ALOX15 (0.44) | CNR1CNR2FAAHMEN1KMT2A | |
| SCHEMBL19026198 | 0.84 | ALOX15 (0.44) | CNR1CNR2FAAHMEN1KMT2A | |
| SCHEMBL16079055 | 0.83 | GSK3B (0.39) | CNR1CNR2MEN1KMT2APOLB | |
| SCHEMBL4761680 | 0.79 | DRD3 (0.36) | CNR1CNR2FAAHPOLBTSHR | |
| SCHEMBL12094076 | 0.79 | RAB9A (0.48) | SMN1; SMN2 | |
| SCHEMBL10148010 | 0.79 | CNR1 (0.38) | CNR1CNR2FAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835556-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2014-09-16 | — | — | US | disclosed |