Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148032 | 0.90 | MEN1 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL4761681 | 0.86 | CNR2 (0.38) | CNR1CNR2SMN1; SMN2HPGDHTT | |
| SCHEMBL13674203 | 0.86 | CNR2 (0.39) | CNR1CNR2HPGDMEN1KMT2A | |
| SCHEMBL11887083 | 0.79 | CKS1B (0.40) | HPGDFAAHMGLL | |
| SCHEMBL16062579 | 0.79 | CNR1 (0.39) | CNR1CNR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13535835 | 0.78 | HPGD (0.38) | CNR1CNR2SMN1; SMN2HPGDHTT | |
| SCHEMBL10148006 | 0.77 | CYP2D6 (0.42) | CNR1CNR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23159269 | 0.77 | HPGD (0.42) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL14016308 | 0.77 | MEN1 (0.48) | SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL10148036 | 0.77 | DRD2 (0.36) | CNR1CNR2SMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106131-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090012241-A1 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7432330-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |