SCHEMBL16063191

SCHEMBL16063191

C=CC(=O)OC(C)COc1ccc(C2(c3ccc(OCC(C)O)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
PDK2 Q15119 3/20 0.35
KMT2A Q03164 4/20 0.34
MEN1 O00255 2/20 0.34
POLB P06746 2/20 0.34
THRB P10828 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
CHRM5 P08912 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
TET3 O43151 1/20 0.31
FBXL19 Q6PCT2 1/20 0.31
CXXC5 Q7LFL8 1/20 0.31
TET1 Q8NFU7 1/20 0.31
KDM2B Q8NHM5 1/20 0.31
CXXC4 Q9H2H0 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2232329 0.96 PDK2 (0.37) LMNAPDK2KMT2AMEN1POLB
SCHEMBL31132446 0.96 PDK2 (0.37) LMNAPDK2KMT2AMEN1POLB
SCHEMBL29028235 0.88 PDK2 (0.35) LMNAPDK2KMT2AMEN1POLB
SCHEMBL14211712 0.87 LMNA (0.41) LMNAPDK2KMT2AMEN1POLB
SCHEMBL29229916 0.86 KMT2A (0.36) LMNAPDK2KMT2AMEN1POLB
SCHEMBL28631614 0.86 PDK2 (0.37) PDK2KMT2AMEN1POLBTHRB
SCHEMBL12916082 0.85 KMT2A (0.38) LMNAPDK2KMT2AMEN1POLB
SCHEMBL2231393 0.85 THRB (0.40) LMNAPDK2KMT2AMEN1POLB
SCHEMBL8405184 0.84 LMNA (0.57) LMNAPDK2KMT2AMEN1POLB
SCHEMBL29441931 0.84 LMNA (0.57) LMNAPDK2KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8835524-B2 Resin precursor composition and resin obtained by photocuring the same NIKON CORPORATION (JP) 2014-09-16 US disclosed