SCHEMBL2232329

SCHEMBL2232329

C=CC(=O)OC(C)COc1ccc(C2(c3ccc(OCC(C)OC(=O)C=C)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.37
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
POLB P06746 1/20 0.37
THRB P10828 1/20 0.36
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CHRM5 P08912 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
MTNR1A P48039 3/20 0.33
MTNR1B P49286 3/20 0.33
TET3 O43151 1/20 0.33
FBXL19 Q6PCT2 1/20 0.33
CXXC5 Q7LFL8 1/20 0.33
TET1 Q8NFU7 1/20 0.33
KDM2B Q8NHM5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31132446 1.00 PDK2 (0.37) PDK2KMT2AMEN1POLBTHRB
SCHEMBL16063191 0.96 LMNA (0.41) PDK2KMT2AMEN1POLBTHRB
SCHEMBL29028235 0.92 PDK2 (0.35) PDK2KMT2AMEN1POLBTHRB
SCHEMBL28631614 0.90 PDK2 (0.37) PDK2KMT2AMEN1POLBTHRB
SCHEMBL2231393 0.89 THRB (0.40) PDK2KMT2AMEN1POLBTHRB
SCHEMBL29229916 0.88 KMT2A (0.36) PDK2KMT2AMEN1POLBTHRB
SCHEMBL12916082 0.87 KMT2A (0.38) PDK2KMT2AMEN1POLBTHRB
SCHEMBL14546503 0.86 THRB (0.42) PDK2KMT2AMEN1POLBTHRB
SCHEMBL28397881 0.85 ESR1 (0.37) PDK2KMT2AMEN1POLBLMNA
SCHEMBL24292229 0.85 KMT2A (0.36) PDK2KMT2AMEN1POLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112444904-B Method for manufacturing polarizing film 日东电工株式会社 2024-07-02 CN disclosed
CN-118251632-A Photosensitive resin composition, cured product, method for producing cured product, organic EL display device, and display device 东丽株式会社 2024-06-25 CN disclosed
CN-111602229-B Support sheet and composite sheet for forming protective film 琳得科株式会社 2024-06-21 CN disclosed
CN-118201912-A Thiophene compound, synthesis method thereof and composition containing thiophene compound 四国化成工业株式会社 2024-06-14 CN disclosed
CN-109789666-B Composite sheet for forming protective film 琳得科株式会社 2024-06-04 CN disclosed
CN-118027840-A Composite sheet for forming protective film 琳得科株式会社 2024-05-14 CN disclosed
CN-111538209-B Photosensitive resin composition, organic EL element partition wall, and organic EL element 日保丽公司 2024-05-14 CN disclosed
CN-117999501-A Polarizing film, image display device, and method for manufacturing polarizing film 日东电工株式会社 2024-05-07 CN disclosed
CN-111587472-B Support sheet and composite sheet for forming protective film 琳得科株式会社 2024-04-30 CN disclosed
CN-117858921-A Resin composition, cured product, organic EL display device, and method for producing cured product 东丽株式会社 2024-04-09 CN disclosed
CN-109154690-A Stacked film and image display device 日东电工株式会社 2019-01-04 CN disclosed
CN-109071693-A Resin combination is used in the formation of high refractive index cured film 日产化学株式会社 2018-12-21 CN disclosed
CN-106029721-B Polymerizable composition containing reactive silsesquioxane compound 日产化学工业株式会社 2018-11-09 CN disclosed
CN-108603953-A Light diffusing agent, light-diffusing resin composition and formed body 三菱瓦斯化学株式会社 2018-09-28 CN disclosed
US-20170334837-A1 DIAMINE COMPOUND, AND HEAT-RESISTANT RESIN OR HEAT-RESISTANT RESIN PRECURSOR USING SAME TORAY INDUSTRIES, INC. (JP) 2017-11-23 US disclosed
EP-2360194-B1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING SAME TORAY INDUSTRIES (JP) 2015-03-11 EP disclosed
US-8835524-B2 Resin precursor composition and resin obtained by photocuring the same NIKON CORPORATION (JP) 2014-09-16 US disclosed
US-8492450-B2 Siloxane resin composition and protective film for touch panel using the same TORAY INDUSTRIES, INC. (JP) 2013-07-23 US disclosed
US-20110230584-A1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING THE SAME TORAY INDUSTRIES, INC. (JP) 2011-09-22 US disclosed
EP-2360194-A1 SILOXANE RESIN COMPOSITION AND PROTECTIVE FILM FOR TOUCH PANEL USING SAME Toray Industries, Inc. (JP) 2011-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334837-A1 DIAMINE COMPOUND, AND HEAT-RESISTANT RESIN OR HEAT-RESISTANT RESIN PRECURSOR USING SAME HEATR1, HSF1, RER1 PDK2 2719/4885KMT2A 1253/4885MEN1 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.