SCHEMBL160646

SCHEMBL160646

O=C(O)c1cc(Cc2ccc(O)c(C(=O)O)c2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 1/20 1.00
CTSB P07858 1/20 1.00
MMP9 P14780 1/20 1.00
DNMT1 P26358 1/20 1.00
DNMT3B Q9UBC3 1/20 1.00
DNMT3L Q9UJW3 1/20 1.00
DNMT3A Q9Y6K1 1/20 1.00
HNF4A P41235 2/20 0.85
LCK P06239 2/20 0.69
ALDH1A1 P00352 2/20 0.62
CDC25B P30305 1/20 0.62
CASP6 P55212 1/20 0.62
RCE1 Q9Y256 1/20 0.62
ACMSD Q8TDX5 3/20 0.62
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
PTGS2 P35354 2/20 0.59
CA12 O43570 1/20 0.59
ALOX5 P09917 1/20 0.59
CA7 P43166 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414416 1.00 KLKB1 (1.00) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL9250700 0.92 KLKB1 (0.85) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL11595273 0.92 KLKB1 (0.85) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL27396608 0.92 HNF4A (1.00) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL5446640 0.92 HNF4A (1.00) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL11133452 0.91 HNF4A (0.96) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL23265352 0.89 KLKB1 (0.79) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL9651461 0.89 KLKB1 (0.79) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL27639966 0.89 KLKB1 (0.79) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL14408665 0.88 KLKB1 (0.77) KLKB1CTSBMMP9DNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2026-02-12 US claimed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
EP-4556112-A2 SORBENT COMPOSITIONS, SYSTEMS, AND METHODS General Electric Technology GmbH (CH) 2025-05-21 EP claimed
US-20250120987-A1 METHOD FOR TREATING CANCER USING HUMAN MITOCHONDRIAL MALIC ENZYME 2 INHIBITOR NATIONAL CHUNG HSING UNIVERSITY (TW) 2025-04-17 US claimed
CN-119242206-A Electrolyte-resistant and high-temperature-resistant lithium battery termination adhesive tape 南京占一科技有限公司 2025-01-03 CN claimed
US-20240199653-A1 METHOD FOR FORMING AN ELECTRICALLY CONDUCTIVE METAL ORGANIC FRAMEWORK COMPOSITE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-06-20 US claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117050613-B Epoxy resin coating for underwater and preparation method thereof 广东千色花新材料有限公司 2024-03-12 CN claimed
CN-117050613-A Epoxy resin coating for underwater and preparation method thereof 广东千色花新材料有限公司 2023-11-14 CN claimed
US-20200291045-A1 CONDUCTIVITY ENHANCEMENT OF MOFS VIA DEVELOPMENT OF MOFPOLYMER COMPOSITE MATERIAL KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-09-17 US claimed
US-4562242-A Branched polycarbonate from carboxy containing diphenol GENERAL ELECTRIC COMPANY (US) 1985-12-31 US claimed
EP-0022701-B1 IMPROVED POLY(ALKYLENE OXIDE) COMPOSITIONS CONTAINING A BRIDGED DIMER OF A HYDROXYLSUBSTITUTED AROMATIC CARBOXYLIC ACID OR A SALT THEREOF UNION CARBIDE CORPORATION (US) 1984-05-23 EP claimed
US-4434066-A HYDROXYL SUBSTITUTED AROMATIC ACID AND NITROAROMATIC COMPOUND FOR LUBRICITY AND WEAR RESISTANCE UNION CARBIDE CORPORATION (US) 1984-02-28 US claimed
US-4385165-A COATING FOR OPTICAL FIBERS SIEMENS AKTIENGESELLSCHAFT (DE) 1983-05-24 US claimed
EP-0027506-B1 PRECURSORS OF POLYIMIDES, POLYISOINDOLOQUINAZOLINE DIONES, POLYOXAZINE DIONES AND POLYQUINAZOLINE DIONES, THEIR PREPARATION AND USE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-05-11 EP claimed
US-4371685-A Radiation-reactive precursor stages of highly heat-resistant polymers SIEMENS AKTIENGESELLSCHAFT (DE) 1983-02-01 US claimed
US-4263167-A CORROSION INHIBITORS FOR FERROUS METALS UNION CARBIDE CORPORATION (US) 1981-04-21 US claimed
US-4159208-A REACTING ALKALI METAL SALT OF AN AROMATIC CARBOXYLIC ACID AND A METAL SALT IN THE PRESENCE OF CLAY AND ALUMINUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-06-26 US claimed
US-4094676-A Non-silver salt type photosensitive composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-06-13 US claimed
US-4001027-A FLUORESCEIN TYPE PIGMENT BORDEN, INC. (US) 1977-01-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP SRMS, TYRO3, SELE KLKB1 1567/4885CTSB 3130/4885MMP9 4178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.