Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712520 | 1.00 | PDK2 (1.00) | PDK2 | |
| SCHEMBL13128786 | 1.00 | PDK2 (1.00) | PDK2 | |
| SCHEMBL13128003 | 0.86 | PDK2 (1.00) | PDK2 | |
| SCHEMBL13128000 | 0.85 | PDK2 (1.00) | PDK2 | |
| SCHEMBL13128788 | 0.84 | PDK2 (1.00) | PDK2 | |
| SCHEMBL1712518 | 0.84 | PDK2 (1.00) | PDK2 | |
| SCHEMBL13434420 | 0.84 | PDK2 (0.78) | PDK2 | |
| SCHEMBL16107285 | 0.84 | PDK2 (0.78) | PDK2 | |
| SCHEMBL16139288 | 0.82 | PDK2 (0.76) | PDK2 | |
| SCHEMBL16769231 | 0.82 | PDK2 (0.76) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805205-A1 | PYRAZOLE-AMIDE COMPOUND AND MEDICINAL USES THEREFOR | Japan Tobacco Inc. (JP) | 2021-04-14 | — | — | EP | disclosed |
| US-20200163937-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2020-05-28 | — | — | US | disclosed |
| US-20180256547-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2018-09-13 | — | — | US | disclosed |
| EP-3348545-A1 | PYRAZOLE-AMIDE COMPOUND AND MEDICINAL USES THEREFOR | Japan Tobacco Inc. (JP) | 2018-07-18 | — | — | EP | disclosed |
| EP-2975028-B1 | PYRAZOLE-AMIDE COMPOUND AND MEDICINAL USES THEREFOR | JAPAN TOBACCO INC (JP) | 2018-02-21 | — | — | EP | disclosed |
| US-20160074364-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2016-03-17 | — | — | US | disclosed |
| US-20160074364-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2016-03-17 | — | — | US | disclosed |
| US-20160074364-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2016-03-17 | — | — | US | disclosed |
| EP-2975028-A1 | PYRAZOLE-AMIDE COMPOUND AND MEDICINAL USES THEREFOR | Japan Tobacco, Inc. (JP) | 2016-01-20 | — | — | EP | disclosed |
| CN-105051015-A | Pyrazole-amide compound and medicinal uses therefor | JAPAN TOBACCO INC | 2015-11-11 | — | — | CN | disclosed |
| US-20150025120-A1 | PYRAZOLE-ALCOHOL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2015-01-22 | — | — | US | disclosed |
| US-20150025120-A1 | PYRAZOLE-ALCOHOL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2015-01-22 | — | — | US | disclosed |
| US-20150025120-A1 | PYRAZOLE-ALCOHOL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2015-01-22 | — | — | US | disclosed |
| US-20140296315-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296316-A1 | HYDRATE AND CRYSTAL OF FLUORENE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296315-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296316-A1 | HYDRATE AND CRYSTAL OF FLUORENE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296315-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296316-A1 | HYDRATE AND CRYSTAL OF FLUORENE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| WO-2014142291-A1 | HYDRATE OF FLUORINE COMPOUND, AND CRYSTALS THEREOF | 日本たばこ産業株式会社 (JP) | 2014-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296315-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | NAT1, CYP2C19, CYP3A5 | PDK2 92/4885 |
| US-20150025120-A1 | PYRAZOLE-ALCOHOL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | ADH5, ADH1A, CYP3A43 | PDK2 18/4885 |
| US-20180256547-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | NAT1, CYP2C19, CYP3A5 | PDK2 92/4885 |
| US-20160074364-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | NAT1, CYP2C19, CYP3A5 | PDK2 92/4885 |
| US-20200163937-A1 | PYRAZOLE-AMIDE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | NAT1, CYP2C19, CYP3A5 | PDK2 92/4885 |
| US-20140296316-A1 | HYDRATE AND CRYSTAL OF FLUORENE COMPOUNDS | AQP1, Q6ZSR9, CFAP20 | PDK2 1135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.