Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CTSC | P53634 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16055948 | 1.00 | SLC6A9 (0.36) | SLC6A9ALDH1A1CTSCCTSLCTSS | |
| SCHEMBL16066042 | 1.00 | SLC6A9 (0.36) | SLC6A9ALDH1A1CTSCCTSLCTSS | |
| SCHEMBL16056849 | 0.81 | KDM1A (0.37) | ALDH1A1MAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL16066005 | 0.81 | KDM1A (0.37) | ALDH1A1MAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL17525850 | 0.81 | KDM1A (0.37) | ALDH1A1MAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL17523294 | 0.77 | HCAR2 (0.40) | SLC6A9ALDH1A1HCAR2MAPTMAPK1 | |
| SCHEMBL17523296 | 0.77 | HCAR2 (0.40) | SLC6A9ALDH1A1HCAR2MAPTMAPK1 | |
| SCHEMBL17525848 | 0.75 | CYP2C9 (0.42) | ALDH1A1MAPTMAPK1GAAHSD17B10 | |
| SCHEMBL16065920 | 0.75 | KDM1A (0.37) | SLC6A9ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL16066007 | 0.75 | ALDH1A1 (0.36) | SLC6A9ALDH1A1SMN1; SMN2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-04-19 | — | — | US | disclosed |
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | UNIV NANYANG TECH (SG) | 2019-11-07 | — | — | US | disclosed |
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-11 | — | — | US | disclosed |
| WO-2014142755-A1 | ACTIVATION OF CARBONYL β-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | SLC6A9 2425/4885ALDH1A1 96/4885CTSC 2547/4885 |
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | SLC6A9 2425/4885ALDH1A1 96/4885CTSC 2547/4885 |
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | CBR1, CBR3, CAT | SLC6A9 2425/4885ALDH1A1 96/4885CTSC 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.