SCHEMBL16067149

SCHEMBL16067149

c1ccc(-c2cccc(-c3nc(-c4cccc(-c5ccccn5)c4)nc(-n4c5ccccc5c5ccc6c7ccccc7c7cc8ccccc8n7c6c54)n3)c2)nc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.37
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
MAPK14 Q16539 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
METAP2 P50579 2/20 0.32
GRM5 P41594 1/20 0.32
NPY5R Q15761 1/20 0.32
KDM4E B2RXH2 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
KAT6A Q92794 1/20 0.31
PRKDC P78527 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033658 0.92 MCL1 (0.37) MCL1HTR1AHTR7MAPK14PIK3CA
SCHEMBL16066866 0.90 MCL1 (0.35) MCL1HTR1AHTR7PIK3CAPIK3CB
SCHEMBL16067179 0.90 MCL1 (0.36) MCL1HTR1AHTR7MAPK14PIK3CA
SCHEMBL16066623 0.89 MCL1 (0.35) MCL1HTR1AHTR7MAPK14PIK3CA
SCHEMBL16067054 0.88 MCL1 (0.36) MCL1HTR1AHTR7MAPK14PIK3CA
SCHEMBL16066218 0.88 GRM5 (0.35) MCL1HTR1AHTR7PIK3CAPIK3CB
SCHEMBL16067195 0.87 GP6 (0.33)
SCHEMBL16066999 0.87 GRM5 (0.34) MCL1HTR1AHTR7PIK3CAPIK3CB
SCHEMBL17033445 0.87 MCL1 (0.35) MCL1HTR1AHTR7MAPK14PIK3CA
SCHEMBL16067171 0.86 HTR1A (0.43) MCL1HTR1AHTR7MAPK14HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014142488-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-09-18 WO disclosed