Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | SRSF6 | Q13247 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868999 | 1.00 | ADRB2 (0.49) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL13865483 | 0.87 | ADRB2 (0.47) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL13865478 | 0.84 | ADRB2 (0.55) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL18218109 | 0.84 | ADRB2 (0.68) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL13868998 | 0.84 | ADRB2 (0.72) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL16066898 | 0.84 | ADRB2 (0.72) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL865931 | 0.83 | ADRB2 (0.45) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL21204863 | 0.80 | ADRB2 (0.66) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL13869000 | 0.79 | ADRB2 (0.71) | ADRB2ADRB1DRD3SLC6A2ADRA1D | |
| SCHEMBL13617868 | 0.79 | ADRB2 (0.47) | ADRB2ADRB1DRD3SLC6A2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139485-A1 | A METHOD FOR THE PREPARATION OF 5-[(R)-2-(5,6-DIETHYL-INDAN-2-YLAMINO)-L-HYDROXYETHYL]- 8-HYDROXY-(1H)-QUINOLIN-2-ONE (INDACATEROL) | ZENTIVA, K.S. (CZ) | 2014-09-18 | — | — | WO | disclosed |