SCHEMBL16070599

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL147207	0.83	PDE2A (0.60)	PDE2ADGAT1APLNRADRB2CYP3A4
	SCHEMBL15688137	0.83	PDE2A (0.40)	PDE2ADGAT1APLNRADRB2CYP3A4
	SCHEMBL7346953	0.81	ADRB2 (0.42)	PDE2ADGAT1APLNRADRB2CYP3A4
	SCHEMBL11899944	0.80	PDE2A (0.45)	PDE2ADGAT1APLNRADRB2CYP3A4
	SCHEMBL12303658	0.80	CES2 (0.49)	PDE2APYGLADRB2CYP3A4HSD17B10
	SCHEMBL15092400	0.79	APLNR (0.44)	PDE2ADGAT1APLNRKDM4E
	SCHEMBL15688148	0.79	APLNR (0.38)	DGAT1APLNRMAPTKDM1AKDM1B
	SCHEMBL12267174	0.79	APLNR (0.44)	PDE2ADGAT1APLNRKDM4E
	SCHEMBL2879129	0.79	APLNR (0.44)	PDE2ADGAT1APLNRKDM4E
	SCHEMBL17927648	0.79	PDE2A (0.44)	PDE2ADGAT1APLNRADRB2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.