Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 12/20 | 0.60 |
| ▸ | RAB9A | P51151 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311709 | 0.89 | TP53 (0.78) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL16073066 | 0.84 | RAB9A (0.60) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL24072273 | 0.80 | TP53 (0.48) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL25142454 | 0.78 | RAB9A (0.76) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL31665068 | 0.78 | RAB9A (0.76) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6318204 | 0.77 | RAB9A (0.68) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4937471 | 0.77 | CASP3 (0.73) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL16073082 | 0.77 | RAB9A (0.70) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL25142625 | 0.76 | RAB9A (0.60) | TP53NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL25063149 | 0.74 | STAT3 (0.64) | TP53NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604946-B2 | Methods for modulating bacterial virulence and related compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-03-28 | — | — | US | disclosed |
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | STAT1, MLEC, CGAS | TP53 2788/4885NPC1 3763/4885RAB9A 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.