Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.78 |
| ▸ | NPC1 | O15118 | 12/20 | 0.66 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 11/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.62 |
| ▸ | FES | P07332 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | GSK3A | P49840 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.62 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.62 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.62 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.62 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.62 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.62 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16073083 | 0.89 | TP53 (0.62) | TP53NPC1KLF5RAB9ASMN1; SMN2 | |
| SCHEMBL6318204 | 0.84 | RAB9A (0.68) | TP53NPC1KLF5RAB9ASMN1; SMN2 | |
| SCHEMBL6769684 | 0.80 | NPC1 (1.00) | TP53NPC1KLF5RAB9ASMN1; SMN2 | |
| SCHEMBL16073069 | 0.76 | RAB9A (0.72) | TP53NPC1KLF5RAB9ASMN1; SMN2 | |
| SCHEMBL6312067 | 0.76 | NPC1 (0.68) | TP53NPC1KLF5RAB9ASMN1; SMN2 | |
| SCHEMBL16073066 | 0.75 | RAB9A (0.60) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5835450 | 0.75 | NPC1 (0.58) | TP53NPC1KLF5RAB9ASMN1; SMN2 | |
| SCHEMBL16078325 | 0.75 | MEN1 (0.62) | TP53NPC1KLF5RAB9ASMN1; SMN2 | |
| SCHEMBL6310452 | 0.74 | NPC1 (0.60) | TP53NPC1KLF5RAB9ASMN1; SMN2 | |
| SCHEMBL17318607 | 0.74 | APOBEC3G (0.66) | TP53NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604946-B2 | Methods for modulating bacterial virulence and related compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-03-28 | — | — | US | disclosed |
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-18 | — | — | US | disclosed |
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | MITSUI CHEMICALS, INC. (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1489073-A1 | PROCESS FORPREPARATION OF ALKOXYBENZAMIDES AND THIAZOLYL ISOCYANATES | MITSUI CHEMICALS, INC. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | STAT1, MLEC, CGAS | TP53 2788/4885NPC1 3763/4885KLF5 1137/4885 |
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | CBR3, CBR1, IDH1 | TP53 3925/4885NPC1 3375/4885KLF5 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.