Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.44 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26263454 | 0.92 | GNAI3 (0.53) | EPHX2EPHX1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL24501935 | 0.88 | EPHX2 (0.43) | EPHX2EPHX1ALDH1A1GNAI3GNAO1 | |
| SCHEMBL4487574 | 0.87 | EPHX2 (0.51) | EPHX2EPHX1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL621450 | 0.85 | EPHX2 (0.50) | EPHX2EPHX1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL4578708 | 0.85 | EPHX2 (0.50) | EPHX2EPHX1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL4518519 | 0.83 | GNAI3 (0.51) | EPHX2EPHX1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL10305557 | 0.83 | EPHX2 (0.49) | EPHX2EPHX1ALDH1A1 | |
| SCHEMBL6029465 | 0.83 | EPHX2 (0.49) | EPHX2EPHX1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL3317695 | 0.83 | EPHX2 (0.49) | EPHX2EPHX1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL15128614 | 0.82 | EPHX2 (0.43) | EPHX2EPHX1ALDH1A1CHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160208046-A1 | AMINE FUNCTIONAL POLYAMIDES | GENZYME CORPORATION | 2016-07-21 | — | — | US | disclosed |
| US-9326994-B2 | Amine functional polyamides | GENZYME CORPORATION (US) | 2016-05-03 | — | — | US | disclosed |
| US-20140275469-A1 | AMINE FUNCTIONAL POLYAMIDES | GENZYME CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160208046-A1 | AMINE FUNCTIONAL POLYAMIDES | PAM, ASNS, PARN | EPHX2 3584/4885EPHX1 4025/4885ALDH1A1 4279/4885 |
| US-20140275469-A1 | AMINE FUNCTIONAL POLYAMIDES | PAM, ASNS, PARN | EPHX2 3584/4885EPHX1 4025/4885ALDH1A1 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.