Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16077702 | 0.88 | EPHX2 (0.51) | EPHX2EPHX1ALDH1A1GNAI3GNAO1 | |
| SCHEMBL22520624 | 0.83 | CACNA2D1 (0.43) | EPHX2HRH3KCNH2EPHX1CYP2D6 | |
| SCHEMBL26269840 | 0.81 | HRH3 (0.43) | EPHX2HRH3KCNH2CYP2D6ALDH1A1 | |
| SCHEMBL26263454 | 0.81 | GNAI3 (0.53) | EPHX2EPHX1ALDH1A1GNAI3GNAO1 | |
| SCHEMBL24475306 | 0.80 | HRH3 (0.42) | EPHX2HRH3KCNH2EPHX1CYP2D6 | |
| SCHEMBL24671522 | 0.80 | HSD11B1 (0.43) | EPHX2HRH3KCNH2CYP2D6ALDH1A1 | |
| SCHEMBL10154480 | 0.80 | HRH3 (0.46) | EPHX2HRH3KCNH2CYP2D6ALDH1A1 | |
| SCHEMBL25480233 | 0.80 | HRH3 (0.44) | HRH3KCNH2CYP2D6 | |
| SCHEMBL24501687 | 0.79 | KDM4E (0.46) | EPHX2HRH3KCNH2CYP2D6ALDH1A1 | |
| SCHEMBL12890856 | 0.78 | HRH3 (0.43) | HRH3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |