Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081355 | 0.80 | ADRB1 (0.55) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL21916490 | 0.73 | ADRB1 (0.55) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL26133050 | 0.73 | ADRB1 (0.55) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL13979172 | 0.73 | ADRB1 (0.67) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Betaxolol SCHEMBL26664793 | 0.70 | ADRB1 (0.90) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL16077977 | 0.69 | ADRB1 (0.54) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL11875628 | 0.69 | ADRB2 (0.53) | ADRB1MEN1KMT2ACYP2D6ADRB2 | |
| Betaxolol SCHEMBL26664771 | 0.69 | ADRB1 (0.86) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Betaxolol SCHEMBL4997902 | 0.69 | ADRB1 (1.00) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Betaxolol SCHEMBL6512495 | 0.69 | ADRB1 (1.00) | ADRB1LMNAMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275091-A1 | Ocular formulations comprising geranylgeranylacetone derivatives for intraocular delivery | COYOTE PHARMACEUTICALS, INC. | 2014-09-18 | — | — | US | disclosed |
| US-20140275281-A1 | Geranylgeranyl acetone and derivatives thereof for intranasal administration | COYOTE PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275281-A1 | Geranylgeranyl acetone and derivatives thereof for intranasal administration | COYOTE PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275091-A1 | Ocular formulations comprising geranylgeranylacetone derivatives for intraocular delivery | COYOTE PHARMACEUTICALS, INC. | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275281-A1 | Geranylgeranyl acetone and derivatives thereof for intranasal administration | GGPS1, NAA50, GAP43 | ADRB1 133/4885LMNA 2669/4885MEN1 1705/4885 |
| US-20140275091-A1 | Ocular formulations comprising geranylgeranylacetone derivatives for intraocular delivery | FNTA, GGPS1, GNPAT | ADRB1 410/4885LMNA 1906/4885MEN1 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.