Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081493 | 0.92 | THRB (0.40) | THRBPTPN2PTPN1PTPN6GAA | |
| SCHEMBL115658 | 0.84 | KIF11 (0.46) | THRBTSHRALDH1A1KIF11TDP1 | |
| SCHEMBL316845 | 0.82 | THRB (0.54) | THRBSMN1; SMN2TSHRKMT2AALDH1A1 | |
| SCHEMBL488918 | 0.81 | THRB (0.53) | THRBSMN1; SMN2TSHRKMT2AALDH1A1 | |
| SCHEMBL7563917 | 0.81 | THRB (0.59) | THRBPTPN2PTPN1PTPN6SMN1; SMN2 | |
| Methacrylic Acid SCHEMBL28158161 | 0.80 | THRB (0.51) | THRBSMN1; SMN2TSHRKMT2AALDH1A1 | |
| SCHEMBL2602455 | 0.79 | THRB (0.49) | THRBSMN1; SMN2GAATSHRALDH1A1 | |
| SCHEMBL24312367 | 0.79 | TDP1 (0.48) | THRBTSHRKIF11TDP1HTT | |
| SCHEMBL28173347 | 0.79 | TDP1 (0.51) | THRBTSHRKIF11TDP1HTT | |
| SCHEMBL8016861 | 0.77 | THRB (0.49) | THRBSMN1; SMN2TSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999623-B2 | Degradable neutral layers for block copolymer lithography applications | WISCOUSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140263164-A1 | DEGRADABLE NEUTRAL LAYERS FOR BLOCK COPOLYMER LITHOGRAPHY APPLICATIONS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-18 | — | — | US | disclosed |