Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 8/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28173347 | 0.97 | TDP1 (0.51) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL115658 | 0.91 | KIF11 (0.46) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1325115 | 0.85 | TSHR (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL12603496 | 0.84 | KIF11 (0.49) | TDP1KIF11TK2TK1HRH4 | |
| SCHEMBL17320926 | 0.81 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL16078201 | 0.79 | THRB (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1404303 | 0.78 | TDP1 (0.68) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL3101729 | 0.78 | TDP1 (0.47) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL3174130 | 0.78 | POLB (0.60) | TDP1POLBAPEX1HTT | |
| SCHEMBL16081493 | 0.78 | THRB (0.40) | TDP1POLBAPEX1HTTKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022071286-A1 | LIQUID-CRYSTAL COMPOSITION, LIQUID-CRYSTAL DISPLAY ELEMENT PRODUCTION METHOD, AND LIQUID-CRYSTAL DISPLAY ELEMENT | 日産化学株式会社 | 2022-04-07 | — | — | WO | disclosed |