Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 12/20 | 0.55 |
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16085610 | 0.86 | SCD (0.65) | SCDABL1LMNAMEN1KMT2A | |
| SCHEMBL16085428 | 0.84 | LMNA (0.57) | SCDABL1LMNAMEN1KMT2A | |
| SCHEMBL16085608 | 0.82 | ABL1 (0.56) | SCDABL1LMNAMEN1KMT2A | |
| SCHEMBL16085425 | 0.81 | SCD (0.61) | SCDABL1LMNAMEN1KMT2A | |
| SCHEMBL16085380 | 0.79 | RAB9A (0.74) | SCDABL1LMNAMEN1KMT2A | |
| SCHEMBL16085539 | 0.78 | LMNA (0.57) | SCDABL1LMNAMEN1KMT2A | |
| SCHEMBL16062238 | 0.77 | LMNA (0.60) | SCDABL1LMNAMEN1KMT2A | |
| SCHEMBL16085525 | 0.77 | LMNA (0.53) | SCDABL1LMNAMEN1KMT2A | |
| SCHEMBL4287355 | 0.76 | SCD (0.52) | SCDABL1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4275892 | 0.76 | SCD (0.51) | SCDABL1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014145642-A9 | NRF2 SMALL MOLECULE INHIBITORS FOR CANCER THERAPY | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-11-13 | — | — | WO | disclosed |
| WO-2014145642-A2 | NRF2 SMALL MOLECULE INHIBITORS FOR CANCER THERAPY | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |
| US-8728631-B2 | Dendrimer compound and organic luminescent device employing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |