SCHEMBL16086567

SCHEMBL16086567

C=CC(=O)OC[C](c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.53
AKT1 P31749 1/20 0.48
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 7/20 0.39
TSHR P16473 4/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 3/20 0.39
TP53 P04637 2/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPK1 P28482 3/20 0.39
KMT2A Q03164 2/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
LMNA P02545 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4410741 0.85 THRB (0.53) THRBAKT1TDP1ALDH1A1TSHR
SCHEMBL17594174 0.84 THRB (0.51) THRBAKT1TDP1ALDH1A1TSHR
SCHEMBL27987238 0.80 THRB (0.55) THRBAKT1TDP1ALDH1A1TSHR
SCHEMBL434163 0.76 THRB (0.65) THRBAKT1TDP1ALDH1A1TSHR
Phthalic Acid SCHEMBL28280832 0.75 THRB (0.50) THRBALDH1A1TSHRCYP3A4HSD17B10
Benzoic Acid SCHEMBL28932601 0.75 MAPT (0.50) THRBAKT1ALDH1A1TSHRMAPK1
SCHEMBL10824309 0.75 THRB (0.58) THRBAKT1TDP1ALDH1A1TSHR
SCHEMBL23926522 0.74 ALDH1A1 (0.56) THRBTDP1ALDH1A1MAPK1KMT2A
SCHEMBL434675 0.74 TDP1 (0.68) THRBAKT1TDP1ALDH1A1TSHR
SCHEMBL22373758 0.74 GAA (0.52) THRBAKT1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2868698-B1 CONDUCTIVE POLYMER COMPOSITION, COATED ARTICLE WHICH IS PROVIDED WITH ANTISTATIC FILM OBTAINED FROM CONDUCTIVE POLYMER COMPOSITION, AND PATTERN FORMING METHOD USING CONDUCTIVE POLYMER COMPOSITION SHINETSU POLYMER CO (JP) 2016-12-07 EP disclosed
EP-2868698-A1 CONDUCTIVE POLYMER COMPOSITION, COATED ARTICLE WHICH IS PROVIDED WITH ANTISTATIC FILM OBTAINED FROM CONDUCTIVE POLYMER COMPOSITION, AND PATTERN FORMING METHOD USING CONDUCTIVE POLYMER COMPOSITION Shin-Etsu Polymer Co. Ltd. (JP) 2015-05-06 EP disclosed
CN-102746467-B Curable composition and process for production of organosilicon compound TOAGOSEI CO LTD 2015-01-14 CN disclosed
EP-2781564-A1 Ink composition for inkjet Fujifilm Corporation (JP) 2014-09-24 EP disclosed