Biphenyl

Biphenyl

SCHEMBL1609089

C1CCC(C2CCCCC2)CC1.N=C=N.N=C=N

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
HSD17B10 Q99714 1/20 0.39
EPHX1 P07099 1/20 0.33
HIF1A Q16665 1/20 0.33
SLC18A3 Q16572 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL11241682 1.00 ALDH1A1 (0.61) ALDH1A1HSD17B10EPHX1HIF1ASLC18A3
Biphenyl SCHEMBL4942278 0.96 ALDH1A1 (0.57) ALDH1A1HSD17B10EPHX1HIF1ASLC18A3
Biphenyl SCHEMBL12497681 0.96 ALDH1A1 (0.57) ALDH1A1HSD17B10EPHX1HIF1ASLC18A3
Carbimide SCHEMBL28002161 0.96 ALDH1A1 (0.67) ALDH1A1HSD17B10
Biphenyl SCHEMBL8071601 0.86 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1ASLC18A3
SCHEMBL61560 0.86 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1ASLC18A3
Biphenyl SCHEMBL15309189 0.86 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1ASLC18A3
Biphenyl SCHEMBL4048778 0.86 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1ASLC18A3
SCHEMBL5201533 0.86 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1ASLC18A3
SCHEMBL11035602 0.86 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1ASLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389165-A1 Diamine Compound, Polyimide Precursor and Polyimide Film Using the Same, and Use Thereof SK IE TECHNOLOGY CO., LTD. (KR) 2022-12-08 US disclosed
CN-106433390-A Curing agent for epoxy anticorrosion primer and preparation method thereof 中海油常州涂料化工研究院有限公司 2017-02-22 CN disclosed
EP-2343973-B1 Prodrugs of Sitagliptin CADILA PHARMACEUTICALS LTD (IN) 2016-02-17 EP disclosed
US-9029567-B2 Hypoglycemic compounds CADILA PHARMACEUTICALS LIMITED (IN) 2015-05-12 US disclosed
US-9024039-B2 Heterocycles and derivatives thereof and methods of manufacture and therapeutic use WOMEN & INFANTS' HOSPITAL OF RHODE ISLAND (US) 2015-05-05 US disclosed
EP-2769978-A1 saxagliptin derivatives Cadila Pharmaceuticals Limited (IN) 2014-08-27 EP disclosed
US-20140045771-A1 NOVEL DIPEPTIDYL PEPTIDASE IV (DP-IV) COMPOUNDS Cadila Corporated Campus (IN) 2014-02-13 US disclosed
US-8563517-B2 Dipeptidyl peptidase IV (DP-IV) compounds CADILA PHARMACEUTICALS LIMITED (IN) 2013-10-22 US disclosed
US-20130150578-A1 NOVEL HYPOGLYCEMIC COMPOUNDS CADILA PHARMACEUTICALS LIMITED (IN) 2013-06-13 US disclosed
EP-2555617-A1 NOVEL HYPOGLYCEMIC COMPOUNDS Cadila Pharmaceuticals Limited (IN) 2013-02-13 EP disclosed
WO-1995019956-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-07-27 WO disclosed
EP-0651739-A1 HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS. BRITISH BIOTECH PHARM (GB) 1995-05-10 EP disclosed
EP-0651738-A1 NATURAL AMINO ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-05-10 EP disclosed
WO-1995009841-A1 HYDROXAMIC ACID DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1995-04-13 WO disclosed
EP-0634998-A1 HYDROXAMIC ACID BASED COLLAGENASE AND CYTOKINE INHIBITORS. BRITISH BIO TECHNOLOGY (GB) 1995-01-25 EP disclosed
WO-1994024140-A1 HYDROXAMIC ACID DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1994-10-27 WO disclosed
WO-1994021625-A1 HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1994-09-29 WO disclosed
WO-1994002446-A1 NATURAL AMINO ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1994-02-03 WO disclosed
WO-1994002447-A1 HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1994-02-03 WO disclosed
WO-1993020047-A1 HYDROXAMIC ACID BASED COLLAGENASE AND CYTOKINE INHIBITORS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389165-A1 Diamine Compound, Polyimide Precursor and Polyimide Film Using the Same, and Use Thereof PUF60, PARG, DDT ALDH1A1 1920/4885HSD17B10 3954/4885EPHX1 3995/4885
US-20140045771-A1 NOVEL DIPEPTIDYL PEPTIDASE IV (DP-IV) COMPOUNDS DPP4, DPP3, DPP7 ALDH1A1 708/4885HSD17B10 1173/4885EPHX1 1311/4885
US-20130150578-A1 NOVEL HYPOGLYCEMIC COMPOUNDS GLP1R, GPR119, IAPP ALDH1A1 818/4885HSD17B10 408/4885EPHX1 4246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.