Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1609089 | 0.96 | ALDH1A1 (0.61) | ALDH1A1HSD17B10SLC18A3EPHX1HIF1A | |
| Biphenyl SCHEMBL11241682 | 0.96 | ALDH1A1 (0.61) | ALDH1A1HSD17B10SLC18A3EPHX1HIF1A | |
| Biphenyl SCHEMBL12497681 | 0.93 | ALDH1A1 (0.57) | ALDH1A1HSD17B10SLC18A3EPHX1HIF1A | |
| Carbimide SCHEMBL28002161 | 0.93 | ALDH1A1 (0.67) | ALDH1A1HSD17B10 | |
| Biphenyl SCHEMBL339539 | 0.84 | ALDH1A1 (0.80) | ALDH1A1HSD17B10SLC18A3EPHX1HIF1A | |
| Biphenyl SCHEMBL8071601 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SLC18A3EPHX1HIF1A | |
| SCHEMBL61560 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SLC18A3EPHX1HIF1A | |
| Biphenyl SCHEMBL4048778 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SLC18A3EPHX1HIF1A | |
| Biphenyl SCHEMBL15309189 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SLC18A3EPHX1HIF1A | |
| SCHEMBL5201533 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SLC18A3EPHX1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080071094-A1 | Process for the preparation of perindopril | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-20 | — | — | US | disclosed |
| US-7291745-B2 | Process for the preparation of perindopril | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-11-06 | — | — | US | disclosed |
| US-20060211867-A1 | Process for the preparation of perindopril | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2006-09-21 | — | — | US | disclosed |
| US-20050171165-A1 | Process for the preparation of perindopril | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211867-A1 | Process for the preparation of perindopril | ACE, PRSS1, CYP2S1 | ALDH1A1 131/4885HSD17B10 308/4885SLC18A3 3442/4885 |
| US-20080071094-A1 | Process for the preparation of perindopril | ACE, PRSS1, CYP2S1 | ALDH1A1 131/4885HSD17B10 308/4885SLC18A3 3442/4885 |
| US-20050171165-A1 | Process for the preparation of perindopril | SPR, QDPR, DPYD | ALDH1A1 112/4885HSD17B10 640/4885SLC18A3 3288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.