SCHEMBL16090921

SCHEMBL16090921

CCN(c1ncncc1C)[C@H](C)COC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LATS1 O95835 1/20 0.32
▸ LATS2 Q9NRM7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30551685 0.66 KDM4E (0.38) —
SCHEMBL11224822 0.66 KDM4E (0.38) —
SCHEMBL16090918 0.65 TP53 (0.47) —
SCHEMBL24861474 0.64 CHEK1 (0.38) —
SCHEMBL24504589 0.60 — —
SCHEMBL1132433 0.60 — —
SCHEMBL23472517 0.60 — —
SCHEMBL9963193 0.59 KDM4E (0.35) —
SCHEMBL17001172 0.58 CRHR1 (0.40) —
SCHEMBL12673791 0.58 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014144169-A1 CARM1 INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2014-09-18 — — WO disclosed
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