Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SCN4A | P35499 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30551685 | 1.00 | KDM4E (0.38) | KDM4EMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL14930912 | 0.82 | LMNA (0.39) | KDM4EMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL20133731 | 0.79 | CYP3A4 (0.37) | KDM4EMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL10766412 | 0.79 | CYP3A4 (0.37) | KDM4EMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL20467009 | 0.78 | CYP3A4 (0.41) | TP53CYP3A4LMNAALDH1A1TSHR | |
| SCHEMBL11389447 | 0.75 | LMNA (0.42) | KDM4EMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL11673976 | 0.73 | LMNA (0.36) | CYP3A4LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6642557 | 0.73 | KDM4E (0.42) | KDM4EMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL17377307 | 0.73 | KDM4E (0.42) | KDM4EMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL10371941 | 0.73 | THRB (0.42) | KDM4EMEN1KMT2ATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073871-A1 | Process for the preparation of N-substituted-N-acylated 2,6-dialkylanilines | CIBA-GEIGY AG (CH) | 1983-03-16 | — | — | EP | disclosed |