⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915284 | 0.77 | KDM4E (0.31) | — | |
| SCHEMBL26570120 | 0.74 | — | — | |
| SCHEMBL20777978 | 0.69 | ADORA2A (0.30) | — | |
| SCHEMBL24861474 | 0.69 | CHEK1 (0.38) | — | |
| SCHEMBL22549549 | 0.66 | HSD17B1 (0.34) | — | |
| SCHEMBL14086582 | 0.65 | — | — | |
| SCHEMBL2742981 | 0.61 | CYP11B1 (0.35) | — | |
| SCHEMBL19412772 | 0.61 | JAK2 (0.40) | — | |
| SCHEMBL16090921 | 0.60 | LATS1 (0.32) | — | |
| SCHEMBL25403717 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |