Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RORA | P35398 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | RORB | Q92753 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PARG | Q86W56 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963428 | 0.82 | PGR (0.61) | KMT2AALDH1A1GAAPLK1PGR | |
| SCHEMBL30485670 | 0.82 | PGR (0.68) | KMT2AALDH1A1PGRRORARORC | |
| SCHEMBL6362477 | 0.82 | PGR (0.68) | KMT2AALDH1A1PGRRORARORC | |
| SCHEMBL17434408 | 0.82 | PARG (0.53) | MEN1KMT2AALDH1A1GAAADORA2A | |
| SCHEMBL29941758 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1GAAPLK1 | |
| SCHEMBL10090172 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1GAAPLK1 | |
| SCHEMBL17434506 | 0.78 | CYP1A2 (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2PARG | |
| SCHEMBL6417860 | 0.78 | CNR2 (0.68) | ALDH1A1PLK1PGRRORARORC | |
| SCHEMBL17242660 | 0.77 | MAPT (0.66) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18837522 | 0.77 | MAPK1 (0.65) | PGRTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014142255-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2014-09-18 | — | — | WO | disclosed |